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Chlorine in PDB 5tc8: Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A

Enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A

All present enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A:
2.4.2.28;

Protein crystallography data

The structure of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A, PDB code: 5tc8 was solved by S.A.Cameron, R.S.Firestone, V.L.Schramm, S.C.Almo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 1.80
Space group P 3 2 1
Cell size a, b, c (Å), α, β, γ (°) 123.065, 123.065, 44.755, 90.00, 90.00, 120.00
R / Rfree (%) 16 / 18

Other elements in 5tc8:

The structure of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A (pdb code 5tc8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A, PDB code: 5tc8:

Chlorine binding site 1 out of 1 in 5tc8

Go back to Chlorine Binding Sites List in 5tc8
Chlorine binding site 1 out of 1 in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Methylthio-Dadme-Immucillin-A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl305

b:13.4
occ:0.33
O A:HOH577 3.0 17.1 0.3
NH1 A:ARG116 3.3 11.9 1.0
CD A:ARG116 3.9 11.4 1.0
CH2 A:TRP189 4.3 15.0 1.0
CZ A:ARG116 4.3 11.8 1.0
O A:HOH523 4.5 12.6 1.0
NE A:ARG116 4.6 11.2 1.0

Reference:

R.S.Firestone, S.A.Cameron, J.M.Karp, V.L.Arcus, V.L.Schramm. Tba To Be Published.
Page generated: Fri Jul 26 17:24:21 2024

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