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Chlorine in PDB 5uc1: Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in AntagonismProtein crystallography data
The structure of Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in Antagonism, PDB code: 5uc1
was solved by
L.C.Pedersen,
J.Min,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in Antagonism
(pdb code 5uc1). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in Antagonism, PDB code: 5uc1: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 5uc1Go back to Chlorine Binding Sites List in 5uc1
Chlorine binding site 1 out
of 4 in the Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in Antagonism
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 5uc1Go back to Chlorine Binding Sites List in 5uc1
Chlorine binding site 2 out
of 4 in the Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in Antagonism
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 5uc1Go back to Chlorine Binding Sites List in 5uc1
Chlorine binding site 3 out
of 4 in the Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in Antagonism
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 5uc1Go back to Chlorine Binding Sites List in 5uc1
Chlorine binding site 4 out
of 4 in the Structural Analysis of Glucocorticoid Receptor Beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist Ru-486: Implication of Helix 12 in Antagonism
Mono view Stereo pair view
Reference:
J.Min,
L.Perera,
J.M.Krahn,
C.M.Jewell,
A.F.Moon,
J.A.Cidlowski,
L.C.Pedersen.
Probing Dominant Negative Behavior of Glucocorticoid Receptor Beta Through A Hybrid Structural and Biochemical Approach. Mol. Cell. Biol. 2018.
Page generated: Sat Dec 12 12:30:54 2020
ISSN: ESSN 1098-5549 PubMed: 29437838 DOI: 10.1128/MCB.00453-17 |
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