Chlorine in PDB 5udc: Crystal Structure of Rsv F A2 Bound to MEDI8897

The structure of Crystal Structure of Rsv F A2 Bound to MEDI8897, PDB code: 5udc was solved by J.S.Mclellan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.14 / 3.45
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	103.780, 126.310, 162.310, 90.00, 102.56, 90.00
R / Rfree (%)	17.5 / 23.2

The binding sites of Chlorine atom in the Crystal Structure of Rsv F A2 Bound to MEDI8897 (pdb code 5udc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Rsv F A2 Bound to MEDI8897, PDB code: 5udc:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Rsv F A2 Bound to MEDI8897


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Rsv F A2 Bound to MEDI8897 within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl612 b:95.8 occ:1.00 O F:GLU294 3.3 0.0 1.0 OD1 F:ASN63 3.5 0.5 1.0 ND2 F:ASN63 3.9 0.8 1.0 CG F:ASN63 4.0 0.9 1.0 CA F:GLU295 4.2 1.0 1.0 NE2 F:GLN94 4.3 0.1 1.0 C F:GLU294 4.4 0.1 1.0 CG2 F:ILE292 4.6 85.2 1.0 CG1 F:VAL90 4.7 0.3 1.0 C F:GLU295 4.8 0.2 1.0 N F:GLU295 4.8 0.9 1.0 CG F:GLU295 4.9 0.7 1.0 CB F:GLU295 5.0 0.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Rsv F A2 Bound to MEDI8897


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Rsv F A2 Bound to MEDI8897 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:1.0 occ:1.00 N A:ALA346 3.4 0.1 1.0 CA A:ALA346 3.9 0.1 1.0 OD1 A:ASN345 4.4 0.5 1.0 C A:ASN345 4.4 0.5 1.0 CG2 A:THR311 4.4 0.2 1.0 CB A:ALA346 4.5 0.6 1.0 CG1 A:VAL308 4.6 0.2 1.0 CA A:ASN345 4.6 0.5 1.0 CG2 A:VAL308 4.9 0.6 1.0

Q.Zhu, J.S.Mclellan, N.L.Kallewaard, N.D.Ulbrandt, S.Palaszynski, J.Zhang, B.Moldt, A.Khan, C.Svabek, J.M.Mcauliffe, D.Wrapp, N.K.Patel, K.E.Cook, B.W.M.Richter, P.C.Ryan, A.Q.Yuan, J.A.Suzich. A Highly Potent Extended Half-Life Antibody As A Potential Rsv Vaccine Surrogate For All Infants. Sci Transl Med V. 9 2017.
ISSN: ESSN 1946-6242
PubMed: 28469033
DOI: 10.1126/SCITRANSLMED.AAJ1928