Chlorine in PDB 5uxe: Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178

Enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178

All present enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178:
1.1.1.205;

Protein crystallography data

The structure of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178, PDB code: 5uxe was solved by N.Maltseva, Y.Kim, R.Mulligan, M.Makowska-Grzyska, M.Gu, D.R.Gollapalli, L.Hedstrom, A.Joachimiak, W.F.Anderson, Center For Structural Genomicsof Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.25 / 2.10
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 127.937, 119.101, 96.971, 90.00, 102.86, 90.00
R / Rfree (%) 17.3 / 22.3

Other elements in 5uxe:

The structure of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 also contains other interesting chemical elements:

Potassium (K) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 (pdb code 5uxe). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178, PDB code: 5uxe:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 5uxe

Go back to Chlorine Binding Sites List in 5uxe
Chlorine binding site 1 out of 4 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:61.4
occ:1.00
 CL A:8LA501 0.0 61.4 1.0
C20 A:8LA501 1.8 54.1 1.0
C19 A:8LA501 2.8 51.0 1.0
C21 A:8LA501 2.9 50.2 1.0
C24 A:8LA501 3.2 48.8 1.0
C C:GLY439 3.2 33.4 1.0
O1 A:8LA501 3.2 47.2 1.0
O C:GLY439 3.3 34.8 1.0
CA C:GLY439 3.4 36.0 1.0
CD2 A:HIS249 3.7 33.2 1.0
O3 A:8LA501 3.7 53.8 1.0
N C:TYR440 3.8 33.6 1.0
O C:VAL23 4.0 52.0 1.0
CD C:PRO25 4.0 43.0 1.0
CB A:HIS249 4.0 37.4 1.0
C18 A:8LA501 4.1 50.5 1.0
C22 A:8LA501 4.1 50.3 1.0
OG C:SER21 4.2 40.0 1.0
CG A:HIS249 4.2 31.2 1.0
CG C:PRO25 4.3 43.1 1.0
CA C:TYR440 4.4 32.1 1.0
C25 A:8LA501 4.6 45.8 1.0
C17 A:8LA501 4.6 50.2 1.0
CB C:SER21 4.7 34.5 1.0
N C:GLY439 4.8 34.8 1.0
NE2 A:HIS249 4.9 29.5 1.0
N C:PRO25 5.0 45.5 1.0

Chlorine binding site 2 out of 4 in 5uxe

Go back to Chlorine Binding Sites List in 5uxe
Chlorine binding site 2 out of 4 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl502

b:54.5
occ:1.00
 CL B:8LA502 0.0 54.5 1.0
C20 B:8LA502 1.8 44.2 1.0
C19 B:8LA502 2.8 41.0 1.0
C21 B:8LA502 2.8 39.8 1.0
O1 B:8LA502 3.1 44.2 1.0
C24 B:8LA502 3.2 45.0 1.0
O A:GLY439 3.3 33.0 1.0
C A:GLY439 3.4 40.0 1.0
O A:VAL23 3.6 48.5 1.0
ND1 B:HIS249 3.6 31.7 1.0
CA A:GLY439 3.7 39.3 1.0
O3 B:8LA502 3.7 43.6 1.0
CB B:HIS249 4.0 35.0 1.0
N A:TYR440 4.0 36.9 1.0
C18 B:8LA502 4.1 37.6 1.0
CD A:PRO25 4.1 53.2 1.0
C22 B:8LA502 4.1 36.2 1.0
OG A:SER21 4.2 41.5 1.0
CG B:HIS249 4.3 28.9 1.0
CG A:PRO25 4.6 52.4 1.0
CA A:TYR440 4.6 33.8 1.0
C17 B:8LA502 4.6 35.5 1.0
CB A:SER21 4.6 42.9 1.0
C25 B:8LA502 4.7 44.1 1.0
CE1 B:HIS249 4.8 25.9 1.0
C A:VAL23 4.8 50.0 1.0
CA A:LEU24 5.0 50.4 1.0

Chlorine binding site 3 out of 4 in 5uxe

Go back to Chlorine Binding Sites List in 5uxe
Chlorine binding site 3 out of 4 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl503

b:47.1
occ:1.00
 CL C:8LA503 0.0 47.1 1.0
C20 C:8LA503 1.8 41.1 1.0
C19 C:8LA503 2.8 39.7 1.0
C21 C:8LA503 2.8 38.7 1.0
O1 C:8LA503 3.1 36.1 1.0
C24 C:8LA503 3.2 39.2 1.0
O D:GLY439 3.3 39.6 1.0
C D:GLY439 3.3 36.4 1.0
CA D:GLY439 3.6 34.8 1.0
O3 C:8LA503 3.7 41.5 1.0
ND1 C:HIS249 3.7 35.9 1.0
N D:TYR440 3.9 33.4 1.0
O D:VAL23 4.0 45.8 1.0
CD D:PRO25 4.0 42.3 1.0
C18 C:8LA503 4.1 39.4 1.0
CB C:HIS249 4.1 34.3 1.0
C22 C:8LA503 4.1 36.4 1.0
CG D:PRO25 4.3 41.3 1.0
OG D:SER21 4.3 38.6 1.0
CG C:HIS249 4.4 36.7 1.0
CA D:TYR440 4.5 38.4 1.0
C17 C:8LA503 4.6 37.9 1.0
C25 C:8LA503 4.6 43.1 1.0
CB D:SER21 4.8 40.7 1.0
CE1 C:HIS249 4.8 26.8 1.0
N D:PRO25 4.9 43.9 1.0
CA D:LEU24 4.9 51.0 1.0
N D:GLY439 4.9 36.3 1.0

Chlorine binding site 4 out of 4 in 5uxe

Go back to Chlorine Binding Sites List in 5uxe
Chlorine binding site 4 out of 4 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl503

b:43.5
occ:1.00
 CL D:8LA503 0.0 43.5 1.0
C20 D:8LA503 1.8 31.4 1.0
C19 D:8LA503 2.8 29.3 1.0
C21 D:8LA503 2.9 33.3 1.0
O1 D:8LA503 3.1 34.2 1.0
C24 D:8LA503 3.2 39.4 1.0
O B:GLY439 3.3 26.1 1.0
C B:GLY439 3.3 28.4 1.0
CD2 D:HIS249 3.6 24.8 1.0
CA B:GLY439 3.6 29.1 1.0
O B:VAL23 3.7 35.0 1.0
O3 D:8LA503 3.7 41.9 1.0
N B:TYR440 3.9 29.4 1.0
CB D:HIS249 4.0 23.0 1.0
OG B:SER21 4.1 32.8 1.0
CD B:PRO25 4.1 35.0 1.0
C18 D:8LA503 4.1 30.7 1.0
CG D:HIS249 4.1 22.7 1.0
C22 D:8LA503 4.2 33.2 1.0
CG B:PRO25 4.4 33.5 1.0
CB B:SER21 4.5 28.6 1.0
CA B:TYR440 4.5 27.7 1.0
C25 D:8LA503 4.6 39.9 1.0
C17 D:8LA503 4.6 30.3 1.0
NE2 D:HIS249 4.8 21.9 1.0
N B:PRO25 4.8 29.1 1.0
C B:VAL23 4.9 37.3 1.0
CA B:LEU24 4.9 39.5 1.0
N B:GLY439 5.0 30.7 1.0

Reference:

N.Maltseva, Y.Kim, R.Mulligan, M.Makowska-Grzyska, M.Gu, D.R.Gollapalli, L.Hedstrom, A.Joachimiak, W.F.Anderson, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 To Be Published.
Page generated: Sat Dec 12 12:32:43 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy