Chlorine in PDB 5vb2: Crystal Structure of the Navab Voltage-Gated Sodium Channel in A Closed Conformation

The structure of Crystal Structure of the Navab Voltage-Gated Sodium Channel in A Closed Conformation, PDB code: 5vb2 was solved by M.J.Lenaeus, W.A.Catterall, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.63 / 3.20
Space group	P 21 2 21
Cell size a, b, c (Å), α, β, γ (°)	125.963, 129.853, 196.128, 90.00, 90.00, 90.00
R / Rfree (%)	23.3 / 26.6

The binding sites of Chlorine atom in the Crystal Structure of the Navab Voltage-Gated Sodium Channel in A Closed Conformation (pdb code 5vb2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Navab Voltage-Gated Sodium Channel in A Closed Conformation, PDB code: 5vb2:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Navab Voltage-Gated Sodium Channel in A Closed Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Navab Voltage-Gated Sodium Channel in A Closed Conformation within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1307 b:80.8 occ:1.00 HE2 C:HIS1239 1.8 0.6 1.0 HE2 D:HIS2239 1.9 0.7 1.0 HE2 A:HIS1239 1.9 0.3 1.0 HE2 B:HIS2239 2.2 0.1 1.0 NE2 C:HIS1239 2.4 0.7 1.0 NE2 D:HIS2239 2.5 0.1 1.0 NE2 A:HIS1239 2.5 0.1 1.0 NE2 B:HIS2239 2.7 0.9 1.0 HD2 A:HIS1239 2.9 0.1 1.0 HD2 B:HIS2239 3.0 0.6 1.0 CD2 A:HIS1239 3.0 0.3 1.0 CD2 B:HIS2239 3.1 0.0 1.0 CD2 D:HIS2239 3.2 0.9 1.0 CD2 C:HIS1239 3.2 0.9 1.0 HD12 A:ILE1243 3.2 0.2 1.0 HD2 D:HIS2239 3.2 0.0 1.0 HD2 C:HIS1239 3.3 0.7 1.0 HD12 B:ILE2243 3.4 0.8 1.0 CE1 C:HIS1239 3.4 0.9 1.0 CE1 D:HIS2239 3.5 0.3 1.0 CE1 A:HIS1239 3.6 0.6 1.0 HE1 C:HIS1239 3.7 0.5 1.0 CE1 B:HIS2239 3.7 0.3 1.0 HD11 A:ILE1243 3.8 0.2 1.0 HE1 D:HIS2239 3.8 1.0 1.0 HD11 B:ILE2243 3.9 0.8 1.0 CD1 A:ILE1243 3.9 0.2 1.0 CD1 B:ILE2243 4.0 0.8 1.0 HG13 D:ILE2243 4.0 0.2 1.0 HE1 A:HIS1239 4.0 0.6 1.0 HE1 B:HIS2239 4.1 0.4 1.0 HD13 A:ILE1243 4.2 0.2 1.0 HD13 B:ILE2243 4.2 0.8 1.0 CG A:HIS1239 4.2 0.2 1.0 CG B:HIS2239 4.2 0.1 1.0 CG D:HIS2239 4.3 0.7 1.0 CG C:HIS1239 4.3 0.1 1.0 ND1 C:HIS1239 4.4 0.2 1.0 ND1 D:HIS2239 4.5 0.3 1.0 ND1 A:HIS1239 4.5 0.5 1.0 ND1 B:HIS2239 4.5 0.5 1.0 HG13 C:ILE1243 4.5 0.9 1.0 CG1 D:ILE2243 4.9 0.9 1.0 HG12 D:ILE2243 4.9 0.2 1.0

M.J.Lenaeus, T.M.Gamal El-Din, C.Ing, K.Ramanadane, R.Pomes, N.Zheng, W.A.Catterall. Structures of Closed and Open States of A Voltage-Gated Sodium Channel. Proc. Natl. Acad. Sci. V. 114 E3051 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 28348242
DOI: 10.1073/PNAS.1700761114