Chlorine in PDB 5vbb: Human Rna Pseudouridylate Synthase Domain Containing 1

The structure of Human Rna Pseudouridylate Synthase Domain Containing 1, PDB code: 5vbb was solved by A.Dong, H.Zeng, J.R.Walker, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.52 / 1.94
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	55.200, 92.440, 88.890, 90.00, 90.00, 90.00
R / Rfree (%)	17.9 / 22.4

The binding sites of Chlorine atom in the Human Rna Pseudouridylate Synthase Domain Containing 1 (pdb code 5vbb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Rna Pseudouridylate Synthase Domain Containing 1, PDB code: 5vbb:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Rna Pseudouridylate Synthase Domain Containing 1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Rna Pseudouridylate Synthase Domain Containing 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:37.8 occ:1.00 H A:ARG177 2.6 35.0 1.0 H A:LEU176 2.6 32.3 1.0 HA A:HIS174 2.7 35.7 1.0 HB2 A:LEU176 2.7 34.6 1.0 O A:HOH408 2.9 49.5 1.0 HG3 A:ARG177 3.0 34.8 1.0 O A:HOH474 3.1 43.3 1.0 HD21 A:LEU208 3.1 35.4 1.0 HD3 A:ARG177 3.1 36.9 1.0 N A:LEU176 3.4 34.7 1.0 C A:HIS174 3.4 37.1 1.0 N A:ARG177 3.5 35.1 1.0 CA A:HIS174 3.5 34.9 1.0 HD2 A:ARG177 3.5 36.6 1.0 CD A:ARG177 3.6 37.2 1.0 CB A:LEU176 3.6 35.1 1.0 HG A:LEU176 3.6 38.3 1.0 CG A:ARG177 3.7 33.2 1.0 HD12 A:LEU176 3.7 43.5 1.0 N A:GLN175 3.7 34.1 1.0 CD2 A:LEU208 3.8 36.0 1.0 HD22 A:LEU208 3.8 36.0 1.0 HB2 A:ARG177 3.8 32.0 1.0 O A:HIS174 3.8 34.9 1.0 H A:GLN175 3.8 34.2 1.0 HD23 A:LEU208 3.8 35.6 1.0 OD2 A:ASP67 3.9 48.7 1.0 CA A:LEU176 3.9 35.5 1.0 CG A:LEU176 4.1 39.6 1.0 H12 A:GOL306 4.1 56.6 1.0 CB A:ARG177 4.2 32.1 1.0 C A:LEU176 4.2 39.2 1.0 C A:GLN175 4.3 36.9 1.0 H A:HIS174 4.3 36.0 1.0 HB3 A:HIS174 4.4 36.1 1.0 CD1 A:LEU176 4.4 43.3 1.0 N A:HIS174 4.4 34.8 1.0 CA A:ARG177 4.5 35.5 1.0 HB3 A:LEU176 4.5 34.4 1.0 CA A:GLN175 4.5 32.6 1.0 HB3 A:GLN175 4.5 32.1 1.0 HG1 A:THR70 4.6 42.6 1.0 CB A:HIS174 4.6 36.0 1.0 HD2 A:HIS174 4.6 40.0 1.0 HG2 A:ARG177 4.6 32.1 1.0 HH11 A:ARG177 4.6 44.2 1.0 O A:HOH475 4.7 44.7 1.0 HD11 A:LEU176 4.8 43.8 1.0 H A:VAL178 4.9 36.0 1.0 O A:HOH451 4.9 50.6 1.0 HA A:LEU176 5.0 34.0 1.0

Chlorine binding site 2 out of 2 in the Human Rna Pseudouridylate Synthase Domain Containing 1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Rna Pseudouridylate Synthase Domain Containing 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl305 b:75.6 occ:1.00 H A:GLN65 2.2 43.9 1.0 HB2 A:HIS64 2.8 42.3 1.0 HB2 A:GLN65 3.1 46.9 1.0 N A:GLN65 3.1 43.3 1.0 HA A:HIS64 3.4 44.7 1.0 HZ1 A:LYS97 3.7 88.9 1.0 CB A:HIS64 3.7 41.4 1.0 O A:HOH482 3.8 55.5 1.0 CA A:HIS64 3.9 42.3 1.0 CB A:GLN65 3.9 47.6 1.0 C A:HIS64 4.0 46.9 1.0 O A:GLN65 4.0 40.5 1.0 CA A:GLN65 4.0 44.6 1.0 HB3 A:HIS64 4.1 41.2 1.0 CG A:GLN65 4.3 69.6 1.0 C A:GLN65 4.4 43.4 1.0 NZ A:LYS97 4.4 88.7 1.0 HD1 A:HIS64 4.5 46.2 1.0 HZ2 A:LYS97 4.5 88.7 1.0 HZ3 A:LYS97 4.5 88.7 1.0 HB3 A:GLN65 4.9 47.8 1.0 CG A:HIS64 4.9 44.2 1.0 HA A:GLN65 5.0 45.4 1.0

H.Zeng, A.Dong, J.R.Walker, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomics Consortium (Sgc). Human Rna Pseudouridylate Synthase Domain Containing 1 To Be Published.