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Chlorine in PDB 5vd2: Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735Enzymatic activity of Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735
All present enzymatic activity of Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735:
2.7.10.2; Protein crystallography data
The structure of Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735, PDB code: 5vd2
was solved by
J.-Y.Zhu,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5vd2:
The structure of Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735
(pdb code 5vd2). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735, PDB code: 5vd2: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5vd2Go back to Chlorine Binding Sites List in 5vd2
Chlorine binding site 1 out
of 2 in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 5vd2Go back to Chlorine Binding Sites List in 5vd2
Chlorine binding site 2 out
of 2 in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Pf- 03814735
Mono view Stereo pair view
Reference:
J.Y.Zhu,
R.A.Cuellar,
N.Berndt,
H.E.Lee,
S.H.Olesen,
M.P.Martin,
J.T.Jensen,
G.I.Georg,
E.Schonbrunn.
Structural Basis of Wee Kinases Functionality and Inactivation By Diverse Small Molecule Inhibitors. J. Med. Chem. V. 60 7863 2017.
Page generated: Sat Dec 12 12:33:59 2020
ISSN: ISSN 1520-4804 PubMed: 28792760 DOI: 10.1021/ACS.JMEDCHEM.7B00996 |
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