Chlorine in PDB 5voh: Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox.

The structure of Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox., PDB code: 5voh was solved by V.Cracan, Z.Grabarek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.89 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	107.264, 96.527, 119.061, 90.00, 116.76, 90.00
R / Rfree (%)	19.2 / 25.5

The binding sites of Chlorine atom in the Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox. (pdb code 5voh). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox., PDB code: 5voh:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl506 b:45.8 occ:1.00 NH2 C:ARG184 2.8 46.1 1.0 NH2 A:ARG184 2.8 49.8 1.0 NE A:ARG181 3.6 40.2 1.0 NH2 A:ARG181 3.8 41.6 1.0 CZ C:ARG184 3.9 52.9 1.0 CZ A:ARG184 4.1 54.4 1.0 CZ A:ARG181 4.1 43.4 1.0 NE C:ARG181 4.2 37.0 1.0 NH1 C:ARG184 4.2 52.9 1.0 CB A:ALA189 4.3 35.0 1.0 NH1 A:ARG184 4.5 55.1 1.0 CD C:ARG181 4.6 35.2 1.0 CD A:ARG181 4.7 33.0 1.0 NE C:ARG184 4.9 50.2 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Engineered Water-Forming Nadph Oxidase (Tpnox) Bound to Nadph. the G159A, D177A, A178R, M179S, P184R Mutant of Lbnox. within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl505 b:76.2 occ:1.00 NE D:ARG181 3.6 35.2 1.0 NH1 D:ARG184 4.1 53.9 1.0 CD D:ARG181 4.2 33.0 1.0 CZ D:ARG181 4.6 39.8 1.0 NH2 D:ARG181 4.6 39.4 1.0 O D:HOH643 4.7 34.4 1.0 NH2 D:ARG184 4.8 50.8 1.0 CZ D:ARG184 4.9 50.1 1.0

V.Cracan, D.V.Titov, H.Shen, Z.Grabarek, V.K.Mootha. A Genetically Encoded Tool For Manipulation of Nadp(+)/Nadph in Living Cells. Nat. Chem. Biol. V. 13 1088 2017.
ISSN: ESSN 1552-4469
PubMed: 28805804
DOI: 10.1038/NCHEMBIO.2454