Chlorine in PDB 5vpb: Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal

The structure of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal, PDB code: 5vpb was solved by Z.Yin, M.Machius, G.Rudenko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.74 / 2.69
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	92.825, 99.261, 49.860, 90.00, 109.40, 90.00
R / Rfree (%)	23.8 / 27.5

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 13;

Binding sites:

The binding sites of Chlorine atom in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal (pdb code 5vpb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 13 binding sites of Chlorine where determined in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal, PDB code: 5vpb:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl401 b:47.6 occ:1.00 HH12 D:ARG288 2.4 43.2 1.0 HH22 D:ARG288 2.9 0.5 1.0 NH1 D:ARG288 3.3 35.6 1.0 HB2 D:CYS285 3.7 36.6 1.0 NH2 D:ARG288 3.7 1.0 1.0 HH11 D:ARG288 3.9 43.2 1.0 CZ D:ARG288 3.9 0.8 1.0 HA D:CYS285 3.9 31.4 1.0 HB2 D:LYS284 4.2 59.3 1.0 HB2 C:CYS172 4.3 56.0 1.0 O D:ALA281 4.3 20.1 1.0 HA C:ALA169 4.3 79.7 1.0 H D:CYS285 4.4 23.4 1.0 N D:CYS285 4.4 19.0 1.0 HH21 D:ARG288 4.4 0.5 1.0 CA D:CYS285 4.5 25.7 1.0 CB D:CYS285 4.5 30.0 1.0 HB1 D:ALA281 4.5 71.0 1.0 HE3 D:LYS284 4.5 83.2 1.0 SG C:CYS172 4.6 49.1 1.0 HA D:ALA281 4.6 36.9 1.0 HB3 C:CYS172 4.7 56.0 1.0 HB1 C:ALA168 4.7 66.3 1.0 CB C:CYS172 4.8 49.0 1.0 HB3 D:LYS284 4.8 59.3 1.0 C D:LYS284 4.9 26.4 1.0 CB D:LYS284 4.9 49.0 1.0 HB3 A:ASP188 5.0 42.2 1.0

Chlorine binding site 2 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl402 b:51.3 occ:1.00 HD21 D:LEU329 3.9 64.0 1.0 HG11 D:VAL328 4.0 29.9 1.0 HH22 C:ARG210 4.3 0.2 1.0 HD23 D:LEU329 4.3 64.0 1.0 HG12 D:VAL328 4.4 29.9 1.0 CD2 D:LEU329 4.6 52.9 1.0 HG2 D:LYS325 4.6 45.6 1.0 CG1 D:VAL328 4.7 24.4 1.0 HD21 C:LEU211 4.8 42.1 1.0 HB D:VAL328 4.8 16.9 1.0 HG D:LEU329 4.8 18.4 1.0 HH12 C:ARG210 5.0 0.9 1.0

Chlorine binding site 3 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl403 b:50.7 occ:1.00 HB3 D:SER315 3.3 27.8 1.0 HD23 D:LEU316 3.3 49.1 1.0 HB2 D:SER315 3.8 27.8 1.0 HD21 D:LEU316 3.9 49.1 1.0 CB D:SER315 4.0 22.7 1.0 CD2 D:LEU316 4.0 40.5 1.0 OE1 D:GLU319 4.2 64.6 1.0 HG D:LEU316 4.5 60.8 1.0 HA D:LEU316 4.5 18.6 1.0 N D:LEU316 4.7 35.8 1.0 C D:SER315 4.7 29.1 1.0 HD22 D:LEU316 4.8 49.1 1.0 H D:LEU316 4.8 43.5 1.0 CG D:LEU316 4.9 50.2 1.0 OG D:SER315 4.9 73.5 1.0

Chlorine binding site 4 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl404 b:60.5 occ:1.00 HH11 D:ARG292 3.0 0.6 1.0 HZ3 D:LYS289 3.0 60.3 1.0 HA D:LYS289 3.3 18.5 1.0 HD3 D:ARG292 3.3 0.4 1.0 HG2 C:ARG173 3.3 55.7 1.0 HE2 D:LYS289 3.4 43.2 1.0 HZ1 D:LYS289 3.4 60.3 1.0 HG3 D:LYS289 3.5 41.3 1.0 HD2 D:ARG292 3.5 0.4 1.0 NZ D:LYS289 3.6 49.8 1.0 HH12 C:ARG173 3.8 0.6 1.0 NH1 C:ARG173 3.8 0.5 1.0 NH1 D:ARG292 3.8 0.0 1.0 CD D:ARG292 3.9 86.6 1.0 HH11 C:ARG173 3.9 0.6 1.0 HA C:ARG173 3.9 81.9 1.0 CE D:LYS289 4.0 35.5 1.0 HB2 D:LYS289 4.0 36.3 1.0 HG21 C:THR180 4.1 33.6 1.0 CA D:LYS289 4.2 14.9 1.0 HH12 D:ARG292 4.2 0.6 1.0 HB3 D:ARG292 4.3 36.1 1.0 CZ C:ARG173 4.3 51.9 1.0 HE D:ARG288 4.3 0.3 1.0 CG D:LYS289 4.3 33.9 1.0 CG C:ARG173 4.3 48.8 1.0 CB D:LYS289 4.3 29.8 1.0 HZ2 D:LYS289 4.4 60.3 1.0 HG2 D:ARG288 4.4 88.3 1.0 HB2 D:ARG292 4.5 36.1 1.0 HG3 C:ARG173 4.6 55.7 1.0 HH22 C:ARG173 4.6 68.8 1.0 NH2 C:ARG173 4.7 56.8 1.0 N D:LYS289 4.7 25.6 1.0 HE3 D:LYS289 4.7 43.2 1.0 CB D:ARG292 4.7 29.6 1.0 CD D:LYS289 4.8 32.5 1.0 CZ D:ARG292 4.8 0.4 1.0 HH21 D:ARG288 4.8 0.5 1.0 NE D:ARG292 4.8 0.6 1.0 CA C:ARG173 4.8 67.8 1.0 NE C:ARG173 4.9 50.4 1.0 HB3 C:ARG173 4.9 82.4 1.0 CB C:ARG173 4.9 68.2 1.0 CG D:ARG292 4.9 61.9 1.0 NE D:ARG288 5.0 0.5 1.0

Chlorine binding site 5 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:55.1 occ:1.00 HA A:ALA169 3.8 0.1 1.0 HB2 A:ALA169 4.2 37.2 1.0 HB2 B:CYS285 4.2 41.2 1.0 HE3 B:LYS284 4.2 92.6 1.0 HB2 B:LYS284 4.3 21.9 1.0 HA B:CYS285 4.3 32.5 1.0 HB1 A:ALA168 4.4 42.6 1.0 HB2 A:CYS172 4.5 76.4 1.0 CA A:ALA169 4.5 89.6 1.0 O B:ALA281 4.6 16.9 1.0 N A:ALA169 4.7 34.8 1.0 HB3 B:LYS284 4.7 21.9 1.0 HB3 A:ALA168 4.7 42.6 1.0 HB1 B:ALA281 4.7 48.8 1.0 HB3 A:CYS172 4.7 76.4 1.0 H B:CYS285 4.8 23.8 1.0 CB A:ALA169 4.8 33.3 1.0 N B:CYS285 4.8 19.4 1.0 OE1 C:GLU192 4.8 79.0 1.0 HA B:ALA281 4.8 18.5 1.0 CA B:CYS285 4.9 26.6 1.0 C A:ALA168 4.9 35.2 1.0 O A:ALA168 4.9 34.3 1.0 CB A:CYS172 4.9 63.2 1.0 CB B:LYS284 5.0 17.8 1.0 CB B:CYS285 5.0 33.9 1.0 H A:ALA169 5.0 38.9 1.0

Chlorine binding site 6 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:52.1 occ:1.00 HH22 A:ARG210 2.6 0.6 1.0 HH21 A:ARG210 2.8 0.6 1.0 NH2 A:ARG210 2.9 87.5 1.0 CZ A:ARG210 3.8 0.8 1.0 HD21 A:LEU211 4.2 82.9 1.0 HH12 A:ARG210 4.3 0.1 1.0 HG11 B:VAL328 4.4 16.0 1.0 NH1 A:ARG210 4.4 0.3 1.0 HD23 A:LEU211 4.6 82.9 1.0 HE A:ARG210 4.6 0.0 1.0 NE A:ARG210 4.6 0.2 1.0 CD2 A:LEU211 4.8 68.6 1.0 HG3 B:LYS325 5.0 49.0 1.0

Chlorine binding site 7 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:67.4 occ:1.00 HD3 B:ARG318 2.8 59.4 1.0 HD21 A:LEU204 2.9 21.8 1.0 HG2 B:ARG318 2.9 56.4 1.0 CD B:ARG318 3.5 49.0 1.0 CG B:ARG318 3.6 46.5 1.0 HG3 B:ARG318 3.7 56.4 1.0 CD2 A:LEU204 3.9 17.7 1.0 HE B:ARG318 4.0 56.7 1.0 HD11 A:LEU204 4.1 42.0 1.0 HD23 A:LEU204 4.1 21.8 1.0 HD2 B:ARG318 4.3 59.4 1.0 NE B:ARG318 4.3 46.8 1.0 HD22 A:LEU204 4.3 21.8 1.0 O B:HOH504 4.4 8.9 1.0 OE2 A:GLU200 4.5 66.4 1.0 HG A:LEU204 4.6 27.9 1.0 CG A:LEU204 4.7 22.8 1.0 CD1 A:LEU204 4.9 34.5 1.0 HG3 A:GLU200 4.9 47.1 1.0 CB B:ARG318 5.0 34.6 1.0

Chlorine binding site 8 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:84.0 occ:1.00 HA B:ALA282 3.5 17.2 1.0 HA A:CYS172 3.5 66.0 1.0 HB2 A:CYS172 4.1 76.4 1.0 HB3 B:CYS285 4.1 41.2 1.0 HB2 B:ALA282 4.2 17.4 1.0 HB2 B:CYS285 4.2 41.2 1.0 CA A:CYS172 4.3 54.5 1.0 SG B:CYS285 4.4 48.1 1.0 CA B:ALA282 4.4 16.7 1.0 CB B:CYS285 4.4 33.9 1.0 N A:CYS172 4.6 33.4 1.0 HB1 B:ALA282 4.6 17.4 1.0 CB B:ALA282 4.6 16.8 1.0 CB A:CYS172 4.7 63.2 1.0 HB2 A:LYS171 4.7 68.1 1.0 HB3 A:LYS171 4.7 68.1 1.0 H A:CYS172 4.8 37.3 1.0 C A:LYS171 4.9 52.2 1.0 O A:LYS171 4.9 38.6 1.0 N B:ALA282 4.9 17.4 1.0

Chlorine binding site 9 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl305 b:70.8 occ:1.00 HH12 C:ARG173 2.8 0.6 1.0 HH22 C:ARG173 3.0 68.8 1.0 HE21 A:GLN184 3.4 84.4 1.0 NE2 A:GLN184 3.5 69.9 1.0 NH1 C:ARG173 3.5 0.5 1.0 HE22 A:GLN184 3.5 84.4 1.0 NH2 C:ARG173 3.7 56.8 1.0 CZ D:ARG292 3.7 0.4 1.0 NH1 D:ARG292 3.7 0.0 1.0 HH12 D:ARG292 3.8 0.6 1.0 NH2 D:ARG292 3.9 1.0 1.0 HG2 A:GLN184 4.0 25.8 1.0 HH22 D:ARG292 4.0 0.3 1.0 CZ C:ARG173 4.0 51.9 1.0 HH11 D:ARG292 4.0 0.6 1.0 CD A:GLN184 4.0 61.2 1.0 HH11 C:ARG173 4.1 0.6 1.0 HH21 B:ARG292 4.1 0.2 1.0 HD2 D:ARG292 4.1 0.4 1.0 NE D:ARG292 4.1 0.6 1.0 HH21 D:ARG292 4.2 0.3 1.0 HH21 C:ARG173 4.3 68.8 1.0 HE D:ARG292 4.5 0.5 1.0 CG A:GLN184 4.5 23.9 1.0 OE1 A:GLN184 4.6 69.0 1.0 NH2 B:ARG292 4.6 93.0 1.0 HH22 B:ARG292 4.6 0.2 1.0 CD D:ARG292 4.7 86.6 1.0 HG3 A:GLN184 4.9 25.8 1.0

Chlorine binding site 10 out of 13 in the Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of Transcription Factor Fosb/Jund Bzip Domain in Its Oxidized Form, Type- I Crystal within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:55.6 occ:1.00 HG2 B:LYS289 2.7 57.4 1.0 HG2 A:ARG173 3.0 75.8 1.0 HG3 B:LYS289 3.0 57.4 1.0 HZ3 B:LYS289 3.2 73.0 1.0 HH11 B:ARG292 3.2 87.1 1.0 CG B:LYS289 3.3 47.3 1.0 HA A:ARG173 3.3 74.9 1.0 HE B:ARG288 3.4 0.2 1.0 HE2 B:LYS289 3.4 73.7 1.0 HA B:LYS289 3.5 14.2 1.0 HG3 B:ARG288 3.7 86.1 1.0 HD3 B:ARG292 3.7 0.5 1.0 NE B:ARG288 3.8 98.0 1.0 NZ B:LYS289 3.8 60.4 1.0 CG A:ARG173 3.9 62.7 1.0 HD2 B:ARG292 3.9 0.5 1.0 HH21 B:ARG288 3.9 0.7 1.0 CE B:LYS289 4.0 61.0 1.0 NH1 B:ARG292 4.0 72.1 1.0 HZ1 B:LYS289 4.1 73.0 1.0 HG3 A:ARG173 4.1 75.8 1.0 HG2 B:ARG288 4.2 86.1 1.0 HH11 A:ARG173 4.2 99.3 1.0 CA A:ARG173 4.2 62.0 1.0 NH1 A:ARG173 4.2 82.3 1.0 CD B:LYS289 4.2 29.8 1.0 HH12 B:ARG292 4.3 87.1 1.0 CD B:ARG292 4.3 91.6 1.0 CG B:ARG288 4.3 71.3 1.0 CA B:LYS289 4.3 14.2 1.0 NH2 B:ARG288 4.3 0.8 1.0 CZ B:ARG288 4.3 0.3 1.0 CB B:LYS289 4.4 14.3 1.0 HH12 A:ARG173 4.4 99.3 1.0 HG21 A:THR180 4.4 28.9 1.0 CB A:ARG173 4.4 56.7 1.0 HB3 A:ARG173 4.5 68.5 1.0 CZ A:ARG173 4.5 46.4 1.0 CD B:ARG288 4.5 84.8 1.0 HZ2 B:LYS289 4.6 73.0 1.0 HD3 B:ARG288 4.6 0.3 1.0 SG A:CYS172 4.7 39.3 1.0 HB3 B:ARG292 4.7 40.6 1.0 N B:LYS289 4.7 16.8 1.0 NE A:ARG173 4.8 37.8 1.0 HD2 B:LYS289 4.8 36.3 1.0 HB2 B:ARG292 4.9 40.6 1.0 HD3 B:LYS289 4.9 36.3 1.0 N A:ARG173 4.9 53.0 1.0 HB3 B:LYS289 4.9 14.4 1.0 HE3 B:LYS289 4.9 73.7 1.0 HH22 B:ARG288 4.9 0.7 1.0 CD A:ARG173 4.9 60.0 1.0 H B:LYS289 4.9 20.7 1.0 HB2 B:LYS289 5.0 14.4 1.0

Z.Yin, M.Machius, E.J.Nestler, G.Rudenko. Activator Protein-1: Redox Switch Controlling Structure and Dna-Binding. Nucleic Acids Res. V. 45 11425 2017.
ISSN: ESSN 1362-4962
PubMed: 28981703
DOI: 10.1093/NAR/GKX795