Chlorine in PDB 5w2o: Crystal Structure of Mycobacterium Tuberculosis Kasa

All present enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Kasa:
2.3.1.41;

The structure of Crystal Structure of Mycobacterium Tuberculosis Kasa, PDB code: 5w2o was solved by G.C.Capodagli, M.B.Neiditch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.56 / 1.80
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	77.389, 77.389, 147.008, 90.00, 90.00, 120.00
R / Rfree (%)	15.4 / 17.9

The structure of Crystal Structure of Mycobacterium Tuberculosis Kasa also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Mycobacterium Tuberculosis Kasa (pdb code 5w2o). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Mycobacterium Tuberculosis Kasa, PDB code: 5w2o:

Chlorine binding site 1 out of 1 in the Crystal Structure of Mycobacterium Tuberculosis Kasa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Mycobacterium Tuberculosis Kasa within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl510 b:26.6 occ:1.00 O A:HOH741 3.1 23.1 1.0 NH2 A:ARG390 3.2 22.2 1.0 NE A:ARG390 3.3 20.0 1.0 N A:ALA386 3.5 19.7 1.0 O A:ALA386 3.6 21.1 1.0 CZ A:ARG390 3.7 23.0 1.0 CA A:VAL385 3.8 19.2 1.0 CG1 A:VAL385 3.9 19.7 1.0 C A:VAL385 4.1 18.9 1.0 CB A:ARG390 4.2 19.9 1.0 CB A:VAL385 4.3 19.4 1.0 CD A:ARG390 4.4 20.3 1.0 C A:ALA386 4.5 20.0 1.0 CG A:ARG390 4.5 21.3 1.0 CG2 A:VAL385 4.6 19.4 1.0 CA A:ALA386 4.6 18.5 1.0 O A:VAL384 4.6 20.7 1.0 O A:GLU388 4.6 21.4 1.0 N A:VAL385 4.9 18.4 1.0

P.Kumar, G.C.Capodagli, D.Awasthi, R.Shrestha, K.Maharaja, P.Sukheja, S.G.Li, D.Inoyama, M.Zimmerman, H.P.Ho Liang, J.Sarathy, M.Mina, G.Rasic, R.Russo, A.L.Perryman, T.Richmann, A.Gupta, E.Singleton, S.Verma, S.Husain, P.Soteropoulos, Z.Wang, R.Morris, G.Porter, G.Agnihotri, P.Salgame, S.Ekins, K.Y.Rhee, N.Connell, V.Dartois, M.B.Neiditch, J.S.Freundlich, D.Alland. Synergistic Lethality of A Binary Inhibitor of Mycobacterium Tuberculosis Kasa. Mbio V. 9 2018.
ISSN: ESSN 2150-7511
PubMed: 30563908
DOI: 10.1128/MBIO.02101-17