Chlorine in PDB 5w5o: Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Enzymatic activity of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
All present enzymatic activity of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.:
2.7.10.2; 2.7.11.1;
2.7.10.2; 2.7.11.1;
Protein crystallography data
The structure of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases., PDB code: 5w5o
was solved by
A.Kreusch,
G.Spraggon,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 47.90 / 2.89 |
| Space group | P 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 80.308, 107.475, 210.193, 90.15, 89.77, 89.96 |
| R / Rfree (%) | 21.7 / 25.2 |
Chlorine Binding Sites:
Pages:
>>> Page 1 <<< Page 2, Binding sites: 11 - 16;Binding sites:
The binding sites of Chlorine atom in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. (pdb code 5w5o). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.In total 16 binding sites of Chlorine where determined in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases., PDB code: 5w5o:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;
Chlorine binding site 1 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 1 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 2 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 2 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 3 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 3 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 4 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 4 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 5 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 5 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 5 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 6 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 6 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 6 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 7 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 7 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 7 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 8 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 8 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 8 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 9 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 9 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 9 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Chlorine binding site 10 out of 16 in 5w5o
Go back to
Chlorine Binding Sites List in 5w5o
Chlorine binding site 10 out
of 16 in the Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 10 of Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. within 5.0Å range:
|
Reference:
X.He,
S.Da Ros,
J.Nelson,
X.Zhu,
T.Jiang,
B.Okram,
S.Jiang,
P.Y.Michellys,
M.Iskandar,
S.Espinola,
Y.Jia,
B.Bursulaya,
A.Kreusch,
M.Y.Gao,
G.Spraggon,
J.Baaten,
L.Clemmer,
S.Meeusen,
D.Huang,
R.Hill,
V.Nguyen-Tran,
J.Fathman,
B.Liu,
T.Tuntland,
P.Gordon,
T.Hollenbeck,
K.Ng,
J.Shi,
L.Bordone,
H.Liu.
Identification of Potent and Selective RIPK2 Inhibitors For the Treatment of Inflammatory Diseases. Acs Med Chem Lett V. 8 1048 2017.
ISSN: ISSN 1948-5875
PubMed: 29057049
DOI: 10.1021/ACSMEDCHEMLETT.7B00258
Page generated: Sat Dec 12 12:35:51 2020
ISSN: ISSN 1948-5875
PubMed: 29057049
DOI: 10.1021/ACSMEDCHEMLETT.7B00258
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