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Chlorine in PDB 5wbn: Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger DomainEnzymatic activity of Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain
All present enzymatic activity of Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain:
3.5.1.98; Protein crystallography data
The structure of Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain, PDB code: 5wbn
was solved by
R.J.Harding,
J.R.Walker,
R.Ferreira De Freitas,
M.Ravichandran,
V.Santhakumar,
M.Schapira,
C.Bountra,
A.M.Edwards,
C.H.Arrowsmith,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5wbn:
The structure of Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain
(pdb code 5wbn). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain, PDB code: 5wbn: Chlorine binding site 1 out of 1 in 5wbnGo back to Chlorine Binding Sites List in 5wbn
Chlorine binding site 1 out
of 1 in the Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2, 3-C]Quinazolin-6-Yl)Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain
Mono view Stereo pair view
Reference:
R.J.Harding,
J.R.Walker,
R.Ferreira De Freitas,
M.Ravichandran,
V.Santhakumar,
M.Schapira,
C.Bountra,
A.M.Edwards,
C.H.Arrowsmith.
Crystal Structure of Fragment 3-(3-Benzyl-2-Oxo-2H-[1,2,4]Triazino[2,3-C]Quinazolin-6-Yl) Propanoic Acid Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain To Be Published.
Page generated: Sat Dec 12 12:36:14 2020
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