Chlorine in PDB 5wn1: APE1 Exonuclease Product Complex

All present enzymatic activity of APE1 Exonuclease Product Complex:
4.2.99.18;

The structure of APE1 Exonuclease Product Complex, PDB code: 5wn1 was solved by B.D.Freudenthal, A.M.Whitaker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.52 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	71.869, 63.528, 90.548, 90.00, 109.43, 90.00
R / Rfree (%)	21.3 / 27

The structure of APE1 Exonuclease Product Complex also contains other interesting chemical elements:

Calcium	(Ca)	1 atom
Sodium	(Na)	2 atoms

The binding sites of Chlorine atom in the APE1 Exonuclease Product Complex (pdb code 5wn1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the APE1 Exonuclease Product Complex, PDB code: 5wn1:

Chlorine binding site 1 out of 1 in the APE1 Exonuclease Product Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of APE1 Exonuclease Product Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:72.0 occ:1.00 N B:GLY113 4.0 63.0 1.0 CA B:GLY113 4.0 60.0 1.0 CD1 B:LEU114 4.0 45.9 1.0 CG B:LEU114 4.2 49.6 1.0 C B:GLY113 4.4 60.8 1.0 CB B:LEU111 4.4 59.3 1.0 CD2 B:LEU111 4.5 58.4 1.0 N B:LEU114 4.5 51.5 1.0 CA B:LYS85 4.7 53.1 1.0 CG B:LYS85 4.8 56.7 1.0 C B:LEU111 4.9 62.8 1.0 CA B:LEU111 4.9 66.2 1.0 CB B:LEU114 5.0 49.0 1.0

A.M.Whitaker, T.S.Flynn, B.D.Freudenthal. Molecular Snapshots of APE1 Proofreading Mismatches and Removing Dna Damage. Nat Commun V. 9 399 2018.
ISSN: ESSN 2041-1723
PubMed: 29374164
DOI: 10.1038/S41467-017-02175-Y