Chlorine in PDB 5xc7: Dengue Virus 4 NS3 Helicase D290A Mutant

The structure of Dengue Virus 4 NS3 Helicase D290A Mutant, PDB code: 5xc7 was solved by C.M.D.Swarbrick, C.Basavannacharya, K.W.K.Chan, S.A.Chan, D.Singh, N.Wei, W.W.Phoo, D.Luo, J.Lescar, S.G.Vasudevan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.43 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	53.045, 92.172, 102.515, 90.00, 90.00, 90.00
R / Rfree (%)	18.9 / 22.8

The binding sites of Chlorine atom in the Dengue Virus 4 NS3 Helicase D290A Mutant (pdb code 5xc7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Dengue Virus 4 NS3 Helicase D290A Mutant, PDB code: 5xc7:

Chlorine binding site 1 out of 1 in the Dengue Virus 4 NS3 Helicase D290A Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Dengue Virus 4 NS3 Helicase D290A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl703 b:52.8 occ:1.00 N A:ARG387 3.0 37.5 1.0 O A:HOH807 3.1 43.9 1.0 OG1 A:THR408 3.1 26.7 1.0 CB A:SER386 3.6 31.3 1.0 CB A:ARG387 3.6 45.5 1.0 CA A:SER386 3.8 32.7 1.0 CB A:THR408 3.8 33.2 1.0 CA A:ARG387 3.9 42.3 1.0 C A:SER386 3.9 37.7 1.0 CG2 A:THR408 4.0 27.6 1.0 NH1 A:ARG387 4.1 76.1 1.0 CZ A:ARG387 4.2 87.3 1.0 NE A:ARG387 4.5 90.6 1.0 OG A:SER386 4.6 39.4 1.0 NH2 A:ARG387 4.6 78.1 1.0 CG1 A:ILE365 4.8 35.1 1.0 CD1 A:ILE365 4.8 40.7 1.0 CB A:ILE410 4.9 29.6 1.0 CG A:ARG387 5.0 53.5 1.0

C.M.D.Swarbrick, C.Basavannacharya, K.W.K.Chan, S.A.Chan, D.Singh, N.Wei, W.W.Phoo, D.Luo, J.Lescar, S.G.Vasudevan. NS3 Helicase From Dengue Virus Specifically Recognizes Viral Rna Sequence to Ensure Optimal Replication Nucleic Acids Res. V. 45 12904 2017.
ISSN: ESSN 1362-4962
PubMed: 29165589
DOI: 10.1093/NAR/GKX1127