|
Chlorine in PDB 5xff: Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L)Enzymatic activity of Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L)
All present enzymatic activity of Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L):
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L), PDB code: 5xff
was solved by
D.Wu,
Y.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L)
(pdb code 5xff). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L), PDB code: 5xff: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5xffGo back to Chlorine Binding Sites List in 5xff
Chlorine binding site 1 out
of 2 in the Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L)
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 5xffGo back to Chlorine Binding Sites List in 5xff
Chlorine binding site 2 out
of 2 in the Crystal Structure of LY2874455 in Complex of FGFR4 Gatekeeper Mutation (V550L)
Mono view Stereo pair view
Reference:
D.Wu,
M.Guo,
X.Min,
S.Dai,
M.Li,
S.Tan,
G.Li,
X.Chen,
Y.Ma,
J.Li,
L.Jiang,
L.Qu,
Z.Zhou,
Z.Chen,
L.Chen,
G.Xu,
Y.Chen.
LY2874455 Potently Inhibits Fgfr Gatekeeper Mutants and Overcomes Mutation-Based Resistance. Chem. Commun. (Camb.) V. 54 12089 2018.
Page generated: Sat Dec 12 12:38:46 2020
ISSN: ESSN 1364-548X PubMed: 30298149 DOI: 10.1039/C8CC07546H |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |