Chlorine in PDB 5xgp: Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution

The structure of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution, PDB code: 5xgp was solved by H.Liu, Z.Li, F.Xu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.86 / 2.08
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	70.131, 70.131, 132.584, 90.00, 90.00, 90.00
R / Rfree (%)	21.4 / 23

The binding sites of Chlorine atom in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution (pdb code 5xgp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 9 binding sites of Chlorine where determined in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution, PDB code: 5xgp:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;

Chlorine binding site 1 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:72.9 occ:1.00 ND2 A:ASN178 3.5 38.3 1.0 CG A:ARG258 3.7 37.2 1.0 CD A:ARG258 3.7 40.8 1.0 NH1 A:ARG258 3.9 42.2 1.0 CB A:ASP177 4.2 52.4 1.0 CB A:ASN257 4.2 41.3 1.0 CG A:ASN178 4.4 48.8 1.0 OD1 A:ASN178 4.5 47.8 1.0 O A:HOH418 4.7 67.2 1.0 OD2 A:ASP177 4.7 78.5 1.0 NE A:ARG258 4.8 39.3 1.0 CZ A:ARG258 4.8 46.8 1.0 CG A:ASN257 4.9 49.9 1.0 ND2 A:ASN257 5.0 47.5 1.0 CA A:ALA174 5.0 42.6 1.0

Chlorine binding site 2 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:41.6 occ:1.00 CD2 A:LEU161 3.6 65.4 1.0 CE A:LYS234 3.6 58.7 1.0 N A:ILE162 3.6 35.3 1.0 NZ A:LYS234 3.9 56.0 1.0 CB A:LEU161 4.1 50.3 1.0 CA A:LEU161 4.1 45.1 1.0 CB A:ILE162 4.3 36.8 1.0 CG A:LEU161 4.4 73.1 1.0 C A:LEU161 4.4 35.5 1.0 CG1 A:ILE162 4.5 52.0 1.0 CA A:ILE162 4.5 40.7 1.0 O A:ILE162 4.6 42.8 1.0 CD1 A:ILE162 4.9 51.9 1.0 CD A:LYS234 4.9 73.1 1.0 CD1 A:LEU161 5.0 63.6 1.0 C A:ILE162 5.0 45.8 1.0

Chlorine binding site 3 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl305 b:81.5 occ:1.00 CG A:PRO240 3.7 63.1 1.0 CD A:PRO240 3.9 67.8 1.0 N A:PRO240 4.0 62.4 1.0 CB A:ARG239 4.2 65.5 1.0 C A:ARG239 4.2 68.2 1.0 CB A:PRO240 4.4 60.2 1.0 CA A:PRO240 4.4 67.1 1.0 O A:ARG239 4.5 60.1 1.0 CA A:ARG239 4.8 59.0 1.0

Chlorine binding site 4 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl306 b:80.9 occ:1.00 N A:LYS190 3.9 49.5 1.0 CB A:LYS190 4.1 69.6 1.0 CE1 A:TYR196 4.1 96.2 1.0 C A:LYS189 4.3 54.3 1.0 O A:LYS188 4.3 58.4 1.0 CA A:LYS189 4.4 67.7 1.0 CD1 A:TYR196 4.4 82.4 1.0 CA A:LYS190 4.5 56.5 1.0 N A:LYS189 4.5 58.7 1.0 C A:LYS188 4.6 59.0 1.0 CD A:LYS190 4.8 82.1 1.0 CG A:LYS188 4.9 61.1 1.0

Chlorine binding site 5 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl307 b:84.0 occ:1.00 CB A:SER155 3.5 77.2 1.0 SG A:CYS115 3.6 75.0 1.0 OG A:SER155 3.6 95.9 1.0 CG2 A:VAL112 3.8 56.0 1.0 CA A:VAL112 3.9 48.2 1.0 CB A:CYS115 4.2 45.6 1.0 CB A:VAL112 4.2 54.5 1.0 CG1 A:VAL112 4.4 47.4 1.0 N A:VAL112 4.4 57.4 1.0 O A:PRO111 4.4 52.3 1.0 CD A:LYS253 4.6 77.8 1.0 C A:PRO111 4.6 54.2 1.0 CA A:SER155 4.9 83.3 1.0 CE A:LYS253 4.9 73.7 1.0

Chlorine binding site 6 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl308 b:93.2 occ:1.00 CB A:LYS253 4.1 64.2 1.0 CB A:LYS255 4.3 45.8 1.0 CD A:LYS253 4.5 77.8 1.0 CB A:CYS156 4.5 80.1 1.0 O A:SER155 4.6 86.0 1.0 N A:CYS156 4.6 78.6 1.0 C A:SER155 4.6 85.0 1.0 CD A:LYS255 4.7 59.2 1.0 CA A:CYS156 4.7 68.8 1.0 CB A:SER155 4.7 77.2 1.0 CG A:LYS253 5.0 72.0 1.0 C A:LYS253 5.0 52.1 1.0 O A:LYS253 5.0 53.4 1.0

Chlorine binding site 7 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl309 b:66.5 occ:1.00 N A:LYS264 3.5 62.6 1.0 CB A:GLN263 3.6 73.2 1.0 CA A:GLN263 3.7 63.6 1.0 CD A:PRO240 3.8 67.8 1.0 CG A:GLN263 3.9 74.4 1.0 C A:GLN263 4.1 58.8 1.0 CB A:LYS264 4.4 84.5 1.0 NE2 A:GLN263 4.5 58.5 1.0 CD A:GLN263 4.5 75.5 1.0 CG A:PRO240 4.5 63.1 1.0 CA A:LYS264 4.5 70.2 1.0 CE1 A:HIS261 4.7 64.0 1.0 O A:HOH435 4.8 57.5 1.0 O A:ARG239 4.8 60.1 1.0

Chlorine binding site 8 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl310 b:59.7 occ:1.00 O A:HOH414 2.9 58.7 1.0 ND2 A:ASN179 3.5 62.0 1.0 CE A:LYS208 3.8 40.0 1.0 O A:ASN179 3.9 44.5 1.0 CA A:GLY210 4.0 41.5 1.0 CA A:ASN179 4.0 45.9 1.0 NZ A:LYS208 4.1 51.6 1.0 C A:ASN179 4.5 46.0 1.0 CG A:LEU211 4.5 63.2 1.0 C A:GLY210 4.5 45.5 1.0 O A:ASN178 4.5 42.5 1.0 CG A:ASN179 4.5 65.1 1.0 CB A:ASN179 4.6 54.6 1.0 CD2 A:LEU211 4.6 54.4 1.0 N A:LEU211 4.8 48.6 1.0 O A:HOH449 5.0 57.9 1.0

Chlorine binding site 9 out of 9 in the Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Structure of Sizzled From Xenopus Laevis at 2.08 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl311 b:62.5 occ:1.00 O A:HOH450 3.7 62.7 1.0 N A:PRO111 3.8 55.8 1.0 C A:ALA110 3.9 51.6 1.0 O A:ALA110 3.9 54.1 1.0 CA A:PRO111 4.0 50.2 1.0 CB A:ALA110 4.0 53.5 1.0 CD A:PRO111 4.2 59.1 1.0 CG A:PRO111 4.2 57.0 1.0 CB A:ALA114 4.5 49.4 1.0 CB A:PRO111 4.6 59.9 1.0 CA A:ALA110 4.6 51.5 1.0 O A:HOH453 4.7 55.6 1.0 O A:HOH506 4.9 59.8 1.0

Q.Bu, Z.Li, J.Zhang, F.Xu, J.Liu, H.Liu. The Crystal Structure of Full-Length Sizzled From Xenopus Laevis Yields Insights Into Wnt-Antagonistic Function of Secreted Frizzled-Related Proteins J. Biol. Chem. V. 292 16055 2017.
ISSN: ESSN 1083-351X
PubMed: 28808056
DOI: 10.1074/JBC.M117.791756