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Chlorine in PDB 5xuj: Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]PyrimidineEnzymatic activity of Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]Pyrimidine
All present enzymatic activity of Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]Pyrimidine:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]Pyrimidine, PDB code: 5xuj
was solved by
Y.Amano,
K.Honbou,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5xuj:
The structure of Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]Pyrimidine also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]Pyrimidine
(pdb code 5xuj). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]Pyrimidine, PDB code: 5xuj: Chlorine binding site 1 out of 1 in 5xujGo back to Chlorine Binding Sites List in 5xuj
Chlorine binding site 1 out
of 1 in the Crystal Structure of PDE10A in Complex with 7-(4-Chlorophenyl)-2- Methylpyrazolo[1,5-A]Pyrimidine
Mono view Stereo pair view
Reference:
A.Chino,
R.Seo,
Y.Amano,
I.Namatame,
W.Hamaguchi,
K.Honbou,
T.Mihara,
M.Yamazaki,
M.Tomishima,
N.Masuda.
Fragment-Based Discovery of Pyrimido[1,2-B]Indazole PDE10A Inhibitors. Chem. Pharm. Bull. V. 66 286 2018.
Page generated: Sat Dec 12 12:39:40 2020
ISSN: ISSN 1347-5223 PubMed: 29491261 DOI: 10.1248/CPB.C17-00836 |
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