Chlorine in PDB 5yke: Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A)

The binding sites of Chlorine atom in the Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A) (pdb code 5yke). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A), PDB code: 5yke:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2001 b:0.3 occ:1.00 CL1 B:GBM2001 0.0 0.3 1.0 C31 B:GBM2001 1.8 0.2 1.0 NH2 B:ARG306 2.7 0.5 1.0 C29 B:GBM2001 2.8 0.5 1.0 C32 B:GBM2001 2.8 0.4 1.0 OD1 B:ASN437 3.1 0.0 1.0 NE B:ARG306 3.3 0.5 1.0 CZ B:ARG306 3.4 0.5 1.0 CG B:ASN437 3.4 0.6 1.0 ND2 B:ASN437 3.8 0.1 1.0 C27 B:GBM2001 4.1 0.5 1.0 C30 B:GBM2001 4.1 0.5 1.0 CD1 B:LEU592 4.2 0.3 1.0 CB B:ASN437 4.2 0.5 1.0 OH B:TYR377 4.4 0.2 1.0 C28 B:GBM2001 4.6 0.3 1.0 CD B:ARG306 4.6 0.5 1.0 NH1 B:ARG306 4.7 0.5 1.0 CE1 B:TYR377 4.7 85.3 1.0 CA B:ASN437 4.8 0.3 1.0 CE B:MET441 4.9 0.9 1.0

Chlorine binding site 2 out of 4 in the Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A) within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl2001 b:0.3 occ:1.00 CL1 D:GBM2001 0.0 0.3 1.0 C31 D:GBM2001 1.8 0.2 1.0 NH2 D:ARG306 2.7 0.5 1.0 C29 D:GBM2001 2.8 0.5 1.0 C32 D:GBM2001 2.8 0.4 1.0 OD1 D:ASN437 3.1 0.0 1.0 NE D:ARG306 3.3 0.5 1.0 CZ D:ARG306 3.4 0.5 1.0 CG D:ASN437 3.4 0.6 1.0 ND2 D:ASN437 3.8 0.1 1.0 C27 D:GBM2001 4.1 0.5 1.0 C30 D:GBM2001 4.1 0.5 1.0 CD1 D:LEU592 4.2 0.3 1.0 CB D:ASN437 4.2 0.5 1.0 OH D:TYR377 4.4 0.2 1.0 C28 D:GBM2001 4.6 0.3 1.0 CD D:ARG306 4.6 0.5 1.0 NH1 D:ARG306 4.7 0.5 1.0 CE1 D:TYR377 4.7 85.3 1.0 CA D:ASN437 4.8 0.3 1.0 CE D:MET441 4.9 0.9 1.0

Chlorine binding site 3 out of 4 in the Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A) within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl2001 b:0.3 occ:1.00 CL1 F:GBM2001 0.0 0.3 1.0 C31 F:GBM2001 1.8 0.2 1.0 NH2 F:ARG306 2.7 0.5 1.0 C29 F:GBM2001 2.8 0.5 1.0 C32 F:GBM2001 2.8 0.4 1.0 OD1 F:ASN437 3.1 0.0 1.0 NE F:ARG306 3.3 0.5 1.0 CZ F:ARG306 3.4 0.5 1.0 CG F:ASN437 3.4 0.6 1.0 ND2 F:ASN437 3.8 0.1 1.0 C27 F:GBM2001 4.1 0.5 1.0 C30 F:GBM2001 4.1 0.5 1.0 CD1 F:LEU592 4.2 0.3 1.0 CB F:ASN437 4.2 0.5 1.0 OH F:TYR377 4.4 0.2 1.0 C28 F:GBM2001 4.6 0.3 1.0 CD F:ARG306 4.6 0.5 1.0 NH1 F:ARG306 4.7 0.5 1.0 CE1 F:TYR377 4.7 85.3 1.0 CA F:ASN437 4.8 0.3 1.0 CE F:MET441 4.9 0.9 1.0

Chlorine binding site 4 out of 4 in the Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Pancreatic Atp-Sensitive Potassium Channel Bound with Glibenclamide and Atpgammas (Focused Refinement on Tm at 4.11A) within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl2001 b:0.3 occ:1.00 CL1 H:GBM2001 0.0 0.3 1.0 C31 H:GBM2001 1.8 0.2 1.0 NH2 H:ARG306 2.7 0.5 1.0 C29 H:GBM2001 2.8 0.5 1.0 C32 H:GBM2001 2.8 0.4 1.0 OD1 H:ASN437 3.1 0.0 1.0 NE H:ARG306 3.3 0.5 1.0 CZ H:ARG306 3.4 0.5 1.0 CG H:ASN437 3.4 0.6 1.0 ND2 H:ASN437 3.8 0.1 1.0 C27 H:GBM2001 4.1 0.5 1.0 C30 H:GBM2001 4.1 0.5 1.0 CD1 H:LEU592 4.2 0.3 1.0 CB H:ASN437 4.2 0.5 1.0 OH H:TYR377 4.4 0.2 1.0 C28 H:GBM2001 4.6 0.3 1.0 CD H:ARG306 4.6 0.5 1.0 NH1 H:ARG306 4.7 0.5 1.0 CE1 H:TYR377 4.7 85.3 1.0 CA H:ASN437 4.8 0.3 1.0 CE H:MET441 4.9 0.9 1.0

J.X.Wu, D.Ding, M.Wang, Y.Kang, X.Zeng, L.Chen. Ligand Binding and Conformational Changes of SUR1 Subunit in Pancreatic Atp-Sensitive Potassium Channels. Protein Cell V. 9 553 2018.
ISSN: ESSN 1674-8018
PubMed: 29594720
DOI: 10.1007/S13238-018-0530-Y