Chlorine in PDB 5zkj: Human Exog-H140A in Complex with Rna/Dna Hybrid Duplex

The structure of Human Exog-H140A in Complex with Rna/Dna Hybrid Duplex, PDB code: 5zkj was solved by C.C.Wu, J.L.J.Lin, H.S.Yuan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.43 / 2.80
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	167.576, 167.576, 105.438, 90.00, 90.00, 120.00
R / Rfree (%)	18.1 / 22.7

The structure of Human Exog-H140A in Complex with Rna/Dna Hybrid Duplex also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the Human Exog-H140A in Complex with Rna/Dna Hybrid Duplex (pdb code 5zkj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Exog-H140A in Complex with Rna/Dna Hybrid Duplex, PDB code: 5zkj:

Chlorine binding site 1 out of 1 in the Human Exog-H140A in Complex with Rna/Dna Hybrid Duplex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Exog-H140A in Complex with Rna/Dna Hybrid Duplex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:79.0 occ:1.00 H B:GLY133 2.3 67.4 1.0 HZ B:PHE168 2.9 67.0 1.0 HA B:VAL132 3.0 72.5 1.0 N B:GLY133 3.2 56.1 1.0 HG13 B:VAL132 3.7 74.4 1.0 CZ B:PHE168 3.8 55.9 1.0 HA2 B:GLY133 3.8 70.2 1.0 CA B:VAL132 3.9 60.4 1.0 C B:VAL132 4.0 62.6 1.0 CA B:GLY133 4.1 58.5 1.0 O B:TYR131 4.2 59.7 1.0 HE1 B:PHE168 4.3 61.0 1.0 H B:GLY135 4.4 69.0 1.0 H B:SER134 4.4 70.5 1.0 H4' C:G4 4.4 80.4 1.0 CG1 B:VAL132 4.5 62.0 1.0 O B:TRP136 4.5 62.6 1.0 HG12 B:VAL132 4.5 74.4 1.0 CE1 B:PHE168 4.5 50.9 1.0 H5' C:G4 4.6 86.4 1.0 HE2 B:PHE168 4.6 73.3 1.0 CE2 B:PHE168 4.7 61.1 1.0 HG22 B:VAL132 4.7 74.6 1.0 CB B:VAL132 4.8 64.7 1.0 O3' C:G4 4.8 80.6 1.0 HA3 B:GLY133 4.8 70.2 1.0 N B:SER134 4.8 58.7 1.0 C B:GLY133 4.8 61.6 1.0 N B:VAL132 4.9 55.9 1.0 C B:TYR131 4.9 55.7 1.0 OP1 C:A5 4.9 73.5 1.0 O5' C:G4 5.0 62.5 1.0

C.C.Wu, J.L.J.Lin, H.F.Yang-Yen, H.S.Yuan. A Unique Exonuclease Exog Cleaves Between Rna and Dna in Mitochondrial Dna Replication. Nucleic Acids Res. V. 47 5405 2019.
ISSN: ESSN 1362-4962
PubMed: 30949702
DOI: 10.1093/NAR/GKZ241