|
Chlorine in PDB 6a84: Tankyrase-2 in Complex with Compound 15DEnzymatic activity of Tankyrase-2 in Complex with Compound 15D
All present enzymatic activity of Tankyrase-2 in Complex with Compound 15D:
2.4.2.30; Protein crystallography data
The structure of Tankyrase-2 in Complex with Compound 15D, PDB code: 6a84
was solved by
H.Niwa,
F.Shirai,
S.Sato,
N.Yoshimoto,
T.Tsumura,
M.Okue,
M.Shirouzu,
H.Seimiya,
T.Umehara,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6a84:
The structure of Tankyrase-2 in Complex with Compound 15D also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Tankyrase-2 in Complex with Compound 15D
(pdb code 6a84). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Tankyrase-2 in Complex with Compound 15D, PDB code: 6a84: Chlorine binding site 1 out of 1 in 6a84Go back to Chlorine Binding Sites List in 6a84
Chlorine binding site 1 out
of 1 in the Tankyrase-2 in Complex with Compound 15D
Mono view Stereo pair view
Reference:
F.Shirai,
T.Tsumura,
Y.Yashiroda,
H.Yuki,
H.Niwa,
S.Sato,
T.Chikada,
Y.Koda,
K.Washizuka,
N.Yoshimoto,
M.Abe,
T.Onuki,
Y.Mazaki,
C.Hirama,
T.Fukami,
H.Watanabe,
T.Honma,
T.Umehara,
M.Shirouzu,
M.Okue,
Y.Kano,
T.Watanabe,
K.Kitamura,
E.Shitara,
Y.Muramatsu,
H.Yoshida,
A.Mizutani,
H.Seimiya,
M.Yoshida,
H.Koyama.
Discovery of Novel Spiroindoline Derivatives As Selective Tankyrase Inhibitors. J. Med. Chem. V. 62 3407 2019.
Page generated: Sat Dec 12 12:43:16 2020
ISSN: ISSN 1520-4804 PubMed: 30883102 DOI: 10.1021/ACS.JMEDCHEM.8B01888 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |