Atomistry » Chlorine » PDB 6ael-6apq » 6ak8
Atomistry »
  Chlorine »
    PDB 6ael-6apq »
      6ak8 »

Chlorine in PDB 6ak8: Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP

Enzymatic activity of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP

All present enzymatic activity of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP:
2.7.7.7;

Protein crystallography data

The structure of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP, PDB code: 6ak8 was solved by Y.K.Chang, W.J.Wu, M.D.Tsai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.74
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 59.750, 68.548, 110.165, 90.00, 90.00, 90.00
R / Rfree (%) 17.4 / 20.1

Other elements in 6ak8:

The structure of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP also contains other interesting chemical elements:

Calcium (Ca) 2 atoms
Sodium (Na) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP (pdb code 6ak8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP, PDB code: 6ak8:

Chlorine binding site 1 out of 1 in 6ak8

Go back to Chlorine Binding Sites List in 6ak8
Chlorine binding site 1 out of 1 in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with Templating Adenine and Incoming Ca-8OXODGTP within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl510

b:27.1
occ:1.00
 OG A:SER458 2.9 23.9 1.0
N A:SER458 3.3 20.2 1.0
O A:HOH688 3.3 26.6 1.0
C1' T:DA7 3.5 23.9 1.0
CB A:SER458 3.5 22.1 1.0
C2' T:DA7 3.5 24.1 1.0
NH2 A:ARG387 3.6 24.0 1.0
O4' T:DA7 3.6 25.2 1.0
C4' T:DA7 3.7 24.2 1.0
CB A:ASN457 3.7 20.0 1.0
CA A:SER458 3.9 20.7 1.0
CG A:ASN457 3.9 20.0 1.0
NE2 A:HIS459 3.9 33.9 1.0
CD2 A:HIS459 4.1 29.3 1.0
C3' T:DA7 4.1 24.3 1.0
ND2 A:ASN457 4.1 23.0 1.0
CE1 A:HIS459 4.2 31.4 1.0
O3' T:DA7 4.3 25.8 1.0
C A:ASN457 4.3 20.6 1.0
N A:HIS459 4.4 21.4 1.0
OD1 A:ASN457 4.4 20.7 1.0
CG A:HIS459 4.4 27.5 1.0
C A:SER458 4.4 21.5 1.0
ND1 A:HIS459 4.5 31.0 1.0
CA A:ASN457 4.5 20.2 1.0
NH2 A:ARG445 4.8 23.1 1.0
NH1 A:ARG445 4.8 22.4 1.0
CZ A:ARG387 4.8 22.3 1.0
N9 T:DA7 4.9 23.9 1.0
O2 A:EDO507 4.9 25.6 1.0
O2 T:DT6 4.9 21.8 1.0
C5' T:DA7 5.0 25.2 1.0

Reference:

Y.K.Chang, Y.P.Huang, X.X.Liu, T.P.Ko, Y.Bessho, Y.Kawano, M.Maestre-Reyna, W.J.Wu, M.D.Tsai. Human Dna Polymerase Mu Can Use A Noncanonical Mechanism For Multiple MN2+-Mediated Functions. J.Am.Chem.Soc. V. 141 8489 2019.
ISSN: ESSN 1520-5126
PubMed: 31067051
DOI: 10.1021/JACS.9B01741
Page generated: Fri Jul 26 22:06:18 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy