Chlorine in PDB 6asv: E. Coli Prpp Synthetase

All present enzymatic activity of E. Coli Prpp Synthetase:
2.7.6.1;

The structure of E. Coli Prpp Synthetase, PDB code: 6asv was solved by J.B.French, W.Zhou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.21
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	104.757, 138.436, 137.438, 90.00, 90.00, 90.00
R / Rfree (%)	17.7 / 21.2

The binding sites of Chlorine atom in the E. Coli Prpp Synthetase (pdb code 6asv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the E. Coli Prpp Synthetase, PDB code: 6asv:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the E. Coli Prpp Synthetase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of E. Coli Prpp Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:49.9 occ:1.00 NE A:ARG49 3.2 60.9 1.0 N C:ILE309 3.2 59.7 1.0 O A:HOH559 3.5 37.0 1.0 NE B:ARG105 3.6 42.7 1.0 NH2 A:ARG49 3.8 64.2 1.0 CA C:SER308 3.8 53.3 1.0 NH2 B:ARG105 3.8 44.8 1.0 CZ A:ARG49 4.0 62.2 1.0 C C:SER308 4.0 55.6 1.0 N C:SER310 4.0 69.4 1.0 CB C:ILE309 4.1 67.9 1.0 CZ B:ARG105 4.1 44.2 1.0 CA C:ILE309 4.1 64.0 1.0 CD A:ARG49 4.2 56.7 1.0 OG C:SER308 4.2 52.6 1.0 OG C:SER310 4.2 75.5 1.0 OD1 A:ASN47 4.3 57.4 1.0 CB C:SER308 4.4 52.4 1.0 CG A:ARG49 4.5 52.5 1.0 CD B:ARG105 4.6 41.6 1.0 C C:ILE309 4.6 64.0 1.0 CG1 C:ILE309 4.6 70.9 1.0 O C:GLU307 4.8 50.2 1.0 CG B:ARG105 4.8 41.1 1.0 O A:ALA80 4.9 40.5 1.0 CB C:SER310 4.9 74.8 1.0 N C:SER308 4.9 53.4 1.0 O B:SER103 4.9 39.4 1.0

Chlorine binding site 2 out of 2 in the E. Coli Prpp Synthetase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of E. Coli Prpp Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:72.4 occ:1.00 NE B:ARG49 3.2 64.2 1.0 NE A:ARG105 3.6 56.5 1.0 NH2 B:ARG49 3.8 68.9 1.0 CZ B:ARG49 3.9 64.9 1.0 CD B:ARG49 4.0 61.8 1.0 NH2 A:ARG105 4.1 58.5 1.0 CZ A:ARG105 4.3 59.3 1.0 CG B:ARG49 4.3 58.2 1.0 CD A:ARG105 4.4 51.4 1.0 CG A:ARG105 4.6 50.0 1.0 OD1 B:ASN47 4.7 57.7 1.0 O B:ALA80 4.8 46.2 1.0 O A:SER103 4.9 40.0 1.0

W.Zhou, A.Tsai, D.A.Dattmore, D.P.Stives, I.Chitrakar, A.M.D'alessandro, S.Patil, K.A.Hicks, J.B.French. Crystal Structure of E. Coli Prpp Synthetase. Bmc Struct. Biol. V. 19 1 2019.
ISSN: ESSN 1472-6807
PubMed: 30646888
DOI: 10.1186/S12900-019-0100-4