Chlorine in PDB 6axt: Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein

The structure of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein, PDB code: 6axt was solved by A.T.Gres, K.A.Kirby, S.G.Sarafianos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.70 / 2.40
Space group	P 6
Cell size a, b, c (Å), α, β, γ (°)	92.407, 92.407, 57.509, 90.00, 90.00, 120.00
R / Rfree (%)	22.4 / 24.3

The structure of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein also contains other interesting chemical elements:

Iodine

(I)

9 atoms

The binding sites of Chlorine atom in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein (pdb code 6axt). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein, PDB code: 6axt:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl310 b:0.5 occ:1.00 O A:HOH419 2.6 56.0 1.0 N A:ARG162 3.3 61.9 1.0 N A:PHE161 3.4 64.4 1.0 CB A:ARG162 3.7 64.9 1.0 CB A:PRO160 3.8 62.8 1.0 CA A:GLN219 3.8 0.0 1.0 C A:PRO160 4.0 64.4 1.0 CB A:PHE161 4.1 58.9 1.0 CA A:PHE161 4.1 62.5 1.0 O A:GLN219 4.1 1.0 1.0 CA A:ARG162 4.1 58.9 1.0 O A:CYS218 4.2 89.3 1.0 CA A:PRO160 4.2 63.5 1.0 C A:PHE161 4.2 60.3 1.0 C A:GLN219 4.4 0.2 1.0 CB A:GLN219 4.5 0.0 1.0 I A:IOD303 4.6 81.7 0.5 N A:GLN219 4.7 94.8 1.0 C A:CYS218 4.7 88.7 1.0 O A:PRO160 4.9 60.4 1.0

Chlorine binding site 2 out of 6 in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl311 b:0.3 occ:1.00 O A:HOH441 2.8 74.4 1.0 O A:HOH440 3.2 70.8 1.0 CD1 A:ILE129 3.7 74.1 1.0 CZ3 A:TRP80 4.3 75.6 1.0 CG1 A:ILE129 4.3 73.8 1.0 CH2 A:TRP80 4.6 73.9 1.0

Chlorine binding site 3 out of 6 in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl312 b:0.1 occ:1.00 CG1 A:ILE124 3.9 92.7 1.0 O A:HOH441 4.3 74.4 1.0 CH2 A:TRP80 4.3 73.9 1.0 CZ2 A:TRP80 4.4 75.2 1.0 CD2 A:HIS84 4.4 78.5 1.0 CD1 A:ILE124 4.6 92.2 1.0 CD A:PRO99 4.8 86.3 1.0 CG2 A:ILE124 4.8 88.4 1.0 NE2 A:HIS84 4.9 77.3 1.0

Chlorine binding site 4 out of 6 in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl313 b:72.7 occ:1.00 O A:HOH413 2.7 59.7 1.0 NH2 A:ARG173 3.5 61.8 1.0 CG A:PRO38 3.6 59.7 1.0 NE A:ARG173 4.3 64.3 1.0 CD A:PRO38 4.3 59.6 1.0 CZ A:ARG173 4.3 61.2 1.0 CB A:PRO38 4.8 55.9 1.0 I A:IOD304 4.9 84.1 0.3 I A:IOD305 5.0 88.2 0.4

Chlorine binding site 5 out of 6 in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl314 b:57.2 occ:0.91 O A:GLY60 2.8 72.8 1.0 CD2 A:HIS62 3.4 65.7 1.0 O A:HOH437 3.5 84.4 1.0 NE2 A:HIS62 3.6 67.3 1.0 CG A:GLU28 3.9 0.6 1.0 C A:GLY60 4.0 68.4 1.0 CG1 A:VAL27 4.2 70.6 1.0 CA A:GLU28 4.2 91.2 1.0 CG1 A:VAL59 4.3 54.0 1.0 N A:GLU28 4.4 83.0 1.0 O A:HOH406 4.5 77.3 1.0 C A:VAL27 4.6 77.2 1.0 CG A:HIS62 4.6 67.5 1.0 N A:GLY60 4.6 59.5 1.0 O A:VAL27 4.6 74.4 1.0 CB A:GLU28 4.6 97.4 1.0 CA A:GLY60 4.8 60.1 1.0 CE1 A:HIS62 4.9 67.3 1.0 N A:GLY61 4.9 68.9 1.0 CB A:VAL27 4.9 73.0 1.0 CA A:GLY61 4.9 67.8 1.0 C A:GLY61 5.0 63.0 1.0

Chlorine binding site 6 out of 6 in the Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Structure of the T58S/T107I/P122A Mutant of the Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl315 b:0.1 occ:1.00 N A:PHE32 3.2 83.9 1.0 CB A:PHE32 3.5 69.1 1.0 CB A:TYR145 3.5 96.1 1.0 CB A:ALA31 3.6 94.9 1.0 CD2 A:TYR145 3.6 0.5 1.0 CA A:PHE32 3.6 73.5 1.0 C A:PHE32 3.7 65.8 1.0 O A:PHE32 3.8 64.4 1.0 O A:HOH409 4.0 57.5 1.0 CG A:TYR145 4.0 0.8 1.0 C A:ALA31 4.2 93.0 1.0 O A:TYR145 4.3 84.7 1.0 CD2 A:PHE32 4.4 67.0 1.0 CG A:PHE32 4.4 70.0 1.0 N A:SER33 4.5 62.5 1.0 CA A:ALA31 4.5 95.5 1.0 CE2 A:TYR145 4.7 0.6 1.0 CA A:TYR145 4.8 86.8 1.0 C A:TYR145 4.8 85.8 1.0 O A:LYS30 4.8 82.9 1.0

M.Novikova, A.T.Gres, K.A.Kirby, S.G.Sarafianos, E.O.Freed. Identification of A Novel Element in Hiv-1 Capsid Critical For Assembly and Maturation To Be Published.