Chlorine in PDB 6b4f: Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex

The structure of Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex, PDB code: 6b4f was solved by D.H.Lin, A.R.Correia, S.W.Cai, F.M.Huber, C.A.Jette, A.Hoelz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.78 / 2.81
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	164.660, 69.710, 93.570, 90.00, 90.66, 90.00
R / Rfree (%)	24.5 / 27.4

The binding sites of Chlorine atom in the Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex (pdb code 6b4f). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex, PDB code: 6b4f:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl703 b:56.0 occ:1.00 HB2 D:ASP383 3.5 0.3 1.0 H D:ASP383 3.5 0.4 1.0 OD2 D:ASP383 3.6 0.3 1.0 HE2 A:HIS600 3.9 63.0 1.0 CG D:ASP383 4.0 0.5 1.0 CB D:ASP383 4.2 98.5 1.0 HA D:THR382 4.3 0.1 1.0 N D:ASP383 4.3 95.3 1.0 HE A:ARG603 4.3 63.1 1.0 HG23 D:THR382 4.4 93.9 1.0 CD2 A:TRP389 4.4 61.1 1.0 HD2 A:HIS600 4.5 46.5 1.0 CG A:TRP389 4.5 68.3 1.0 HB2 A:TRP389 4.5 80.9 1.0 CE3 A:TRP389 4.5 57.8 1.0 NE2 A:HIS600 4.6 52.4 1.0 NE A:ARG603 4.6 52.5 1.0 HE3 A:TRP389 4.7 69.4 1.0 HB3 A:TRP389 4.7 80.9 1.0 CE2 A:TRP389 4.7 57.4 1.0 HG22 D:THR382 4.8 93.9 1.0 OD1 D:ASP383 4.8 0.9 1.0 HD3 A:ARG603 4.8 62.0 1.0 HH11 A:ARG603 4.8 68.7 1.0 CD2 A:HIS600 4.9 38.6 1.0 CB A:TRP389 4.9 67.3 1.0 CA D:ASP383 4.9 0.4 1.0 CD1 A:TRP389 4.9 69.2 1.0 HB3 D:ASP383 5.0 0.3 1.0 CZ A:ARG603 5.0 57.4 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human GLE1 Ctd-NUP42 Gbm Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl501 b:44.0 occ:1.00 OD1 C:ASP383 3.2 89.1 1.0 CG C:ASP383 4.1 87.6 1.0 OD2 C:ASP383 4.2 93.9 1.0 HD3 B:ARG603 4.3 23.3 1.0 HE B:ARG603 4.4 25.6 1.0 HD2 B:ARG603 4.4 23.3 1.0 HA B:THR386 4.5 52.8 1.0 H C:ASP383 4.5 88.7 1.0 NE B:ARG603 4.5 21.2 1.0 CE3 B:TRP389 4.6 49.6 1.0 CD2 B:TRP389 4.6 48.4 1.0 HE3 B:TRP389 4.6 59.6 1.0 HE2 B:HIS600 4.6 51.7 1.0 CD B:ARG603 4.6 19.3 1.0 HB3 B:TRP389 4.7 54.2 1.0 HB2 B:TRP389 4.7 54.2 1.0 HG23 B:THR386 4.8 61.9 1.0 CG B:TRP389 4.8 49.1 1.0 HD2 B:HIS600 4.8 38.2 1.0 HG23 C:THR382 4.8 74.1 1.0 OG1 B:THR386 4.9 44.0 1.0 CB B:TRP389 5.0 45.0 1.0

D.H.Lin, A.R.Correia, S.W.Cai, F.M.Huber, C.A.Jette, A.Hoelz. Structural and Functional Analysis of Mrna Export Regulation By the Nuclear Pore Complex. Nat Commun V. 9 2319 2018.
ISSN: ESSN 2041-1723
PubMed: 29899397
DOI: 10.1038/S41467-018-04459-3