Chlorine in PDB 6bql: Crystal Structure of the Human CAMKK2B in Complex with Tae-226

All present enzymatic activity of Crystal Structure of the Human CAMKK2B in Complex with Tae-226:
2.7.11.17;

The structure of Crystal Structure of the Human CAMKK2B in Complex with Tae-226, PDB code: 6bql was solved by R.M.Counago, G.P.De Souza, C.V.Dos Reis, P.Z.Ramos, D.Drewry, K.B.Massirer, P.Arruda, A.M.Edwards, J.M.Elkins, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.94 / 2.00
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	73.738, 73.738, 123.883, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 22.5

The binding sites of Chlorine atom in the Crystal Structure of the Human CAMKK2B in Complex with Tae-226 (pdb code 6bql). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Human CAMKK2B in Complex with Tae-226, PDB code: 6bql:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the Human CAMKK2B in Complex with Tae-226


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Human CAMKK2B in Complex with Tae-226 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:33.1 occ:1.00 CL5 A:BI9501 0.0 33.1 1.0 C5 A:BI9501 1.7 29.9 1.0 C6 A:BI9501 2.7 29.4 1.0 C4 A:BI9501 2.7 29.8 1.0 NAE A:BI9501 3.0 27.6 1.0 OAI A:BI9501 3.7 31.3 1.0 CD1 A:LEU319 3.8 34.4 1.0 CG A:PHE267 3.8 28.2 1.0 CB A:PHE267 3.8 27.8 1.0 CD1 A:PHE267 4.0 29.5 1.0 N1 A:BI9501 4.0 29.2 1.0 N3 A:BI9501 4.0 28.5 1.0 CB A:ALA192 4.3 28.6 1.0 CG2 A:VAL249 4.3 32.2 1.0 CD2 A:PHE267 4.3 29.0 1.0 CAJ A:BI9501 4.4 31.5 1.0 C2 A:BI9501 4.4 30.2 1.0 CE1 A:PHE267 4.6 29.5 1.0 CAO A:BI9501 4.6 35.0 1.0 O A:GLU268 4.7 30.4 1.0 CE2 A:PHE267 5.0 30.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the Human CAMKK2B in Complex with Tae-226


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Human CAMKK2B in Complex with Tae-226 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl503 b:37.5 occ:1.00 OG A:SER316 3.2 30.4 1.0 N A:SER316 3.3 27.9 1.0 CB A:SER316 3.5 28.4 1.0 CD A:PRO315 3.6 25.2 1.0 CG2 A:VAL278 3.9 41.1 1.0 N A:PRO315 3.9 24.9 1.0 CD A:LYS314 3.9 28.7 1.0 CA A:SER316 4.0 27.9 1.0 CB A:LYS314 4.0 26.7 1.0 CG A:LYS314 4.0 27.6 1.0 CB A:VAL278 4.1 41.7 1.0 CB A:PRO315 4.2 25.8 1.0 C A:PRO315 4.2 27.0 1.0 CG A:PRO315 4.2 25.6 1.0 CA A:PRO315 4.3 26.1 1.0 O A:HOH636 4.3 46.5 1.0 CZ A:PHE353 4.4 25.5 1.0 C A:LYS314 4.4 25.7 1.0 N A:VAL278 4.5 40.9 1.0 CE1 A:PHE353 4.5 26.0 1.0 O A:MET276 4.7 37.3 1.0 CE A:LYS314 4.7 29.9 1.0 CA A:LYS314 4.8 25.7 1.0 CA A:VAL278 5.0 40.6 1.0

R.M.Counago, G.P.De Souza, C.V.Dos Reis, D.Drewry, K.B.Massirer, P.Arruda, A.M.Edwards, J.M.Elkins, Structural Genomics Consortium (Sgc). Crystal Structure of the Human CAMKK2B in Complex with Tae-226 To Be Published.