Chlorine in PDB 6bsi: Structure of Hiv-1 Rt Complexed with An Rna/Dna Hybrid Containing the Polypurine-Tract Sequence

The structure of Structure of Hiv-1 Rt Complexed with An Rna/Dna Hybrid Containing the Polypurine-Tract Sequence, PDB code: 6bsi was solved by L.Tian, M.Kim, W.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.30 / 3.25
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	163.850, 163.850, 129.570, 90.00, 90.00, 120.00
R / Rfree (%)	19.3 / 24.1

The structure of Structure of Hiv-1 Rt Complexed with An Rna/Dna Hybrid Containing the Polypurine-Tract Sequence also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Calcium	(Ca)	2 atoms

The binding sites of Chlorine atom in the Structure of Hiv-1 Rt Complexed with An Rna/Dna Hybrid Containing the Polypurine-Tract Sequence (pdb code 6bsi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Hiv-1 Rt Complexed with An Rna/Dna Hybrid Containing the Polypurine-Tract Sequence, PDB code: 6bsi:

Chlorine binding site 1 out of 1 in the Structure of Hiv-1 Rt Complexed with An Rna/Dna Hybrid Containing the Polypurine-Tract Sequence


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Hiv-1 Rt Complexed with An Rna/Dna Hybrid Containing the Polypurine-Tract Sequence within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:99.0 occ:1.00 CL A:EFZ601 0.0 99.0 1.0 C4 A:EFZ601 1.7 93.3 1.0 C3 A:EFZ601 2.5 95.2 1.0 C5 A:EFZ601 2.6 80.7 1.0 CB A:LEU234 3.5 83.2 1.0 O A:LEU234 3.6 87.9 1.0 CD2 A:PHE227 3.7 85.8 1.0 O A:HIS235 3.8 96.3 1.0 CG1 A:VAL106 3.8 86.1 1.0 C2 A:EFZ601 3.9 91.3 1.0 C A:LEU234 3.9 92.9 1.0 C6 A:EFZ601 3.9 82.7 1.0 CB A:VAL106 4.1 80.7 1.0 CD1 A:LEU234 4.1 78.9 1.0 CG2 A:VAL106 4.2 91.7 1.0 C A:HIS235 4.2 99.2 1.0 CE2 A:PHE227 4.3 86.9 1.0 CA A:LEU234 4.3 88.9 1.0 CG A:LEU234 4.5 80.6 1.0 N A:HIS235 4.5 94.9 1.0 OH A:TYR318 4.6 91.9 1.0 C1 A:EFZ601 4.7 89.2 1.0 CG A:PHE227 4.7 80.5 1.0 CA A:HIS235 4.7 91.9 1.0 N A:PRO236 4.7 97.7 1.0 CB A:PHE227 4.9 80.3 1.0 CA A:PRO236 4.9 93.8 1.0

L.Tian, M.S.Kim, H.Li, J.Wang, W.Yang. Structure of Hiv-1 Reverse Transcriptase Cleaving Rna in An Rna/Dna Hybrid. Proc. Natl. Acad. Sci. V. 115 507 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29295939
DOI: 10.1073/PNAS.1719746115