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Chlorine in PDB 6bvi: Ras:Sos:Ras in Complex with A Small Molecule ActivatorProtein crystallography data
The structure of Ras:Sos:Ras in Complex with A Small Molecule Activator, PDB code: 6bvi
was solved by
J.Phan,
J.Abbott,
S.W.Fesik,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6bvi:
The structure of Ras:Sos:Ras in Complex with A Small Molecule Activator also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Ras:Sos:Ras in Complex with A Small Molecule Activator
(pdb code 6bvi). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Ras:Sos:Ras in Complex with A Small Molecule Activator, PDB code: 6bvi: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6bviGo back to Chlorine Binding Sites List in 6bvi
Chlorine binding site 1 out
of 2 in the Ras:Sos:Ras in Complex with A Small Molecule Activator
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6bviGo back to Chlorine Binding Sites List in 6bvi
Chlorine binding site 2 out
of 2 in the Ras:Sos:Ras in Complex with A Small Molecule Activator
Mono view Stereo pair view
Reference:
J.R.Abbott,
T.R.Hodges,
R.N.Daniels,
P.A.Patel,
J.P.Kennedy,
J.E.Howes,
D.T.Akan,
M.C.Burns,
J.Sai,
T.Sobolik,
Y.Beesetty,
T.Lee,
O.W.Rossanese,
J.Phan,
A.G.Waterson,
S.W.Fesik.
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate Ras Signaling. J. Med. Chem. V. 61 6002 2018.
Page generated: Sat Dec 12 12:47:42 2020
ISSN: ISSN 1520-4804 PubMed: 29856609 DOI: 10.1021/ACS.JMEDCHEM.8B00360 |
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