Chlorine in PDB 6cdr: Human CTBP1 (28-378)

The structure of Human CTBP1 (28-378), PDB code: 6cdr was solved by W.E.Royer, A.G.Bellesis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.26 / 2.40
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	89.218, 89.218, 164.233, 90.00, 90.00, 120.00
R / Rfree (%)	23.5 / 26.2

The binding sites of Chlorine atom in the Human CTBP1 (28-378) (pdb code 6cdr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human CTBP1 (28-378), PDB code: 6cdr:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human CTBP1 (28-378)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human CTBP1 (28-378) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:42.9 occ:1.00 HE2 A:HIS315 2.3 41.7 1.0 HH12 A:ARG266 2.6 44.0 1.0 HH22 A:ARG266 2.6 46.7 1.0 NE2 A:HIS315 3.2 34.8 1.0 H4N A:NAI401 3.3 41.8 1.0 NH1 A:ARG266 3.4 36.7 1.0 NH2 A:ARG266 3.4 38.9 1.0 C3N A:NAI401 3.6 33.3 1.0 HH22 A:ARG97 3.7 49.9 1.0 C2N A:NAI401 3.8 32.1 1.0 CZ A:ARG266 3.8 36.3 1.0 C4N A:NAI401 3.9 34.9 1.0 C7N A:NAI401 3.9 32.9 1.0 H71N A:NAI401 4.0 39.9 1.0 HH11 A:ARG266 4.0 44.0 1.0 CE1 A:HIS315 4.1 37.2 1.0 HH21 A:ARG266 4.1 46.7 1.0 H2N A:NAI401 4.1 38.5 1.0 N7N A:NAI401 4.1 33.2 1.0 HE1 A:HIS315 4.1 44.6 1.0 HH21 A:ARG97 4.2 49.9 1.0 CD2 A:HIS315 4.2 35.0 1.0 N1N A:NAI401 4.2 31.9 1.0 HD2 A:HIS315 4.2 42.0 1.0 H A:GLY101 4.2 43.9 1.0 NH2 A:ARG97 4.3 41.6 1.0 C5N A:NAI401 4.3 34.0 1.0 H21 A:EDO404 4.3 41.8 1.0 HO2 A:EDO404 4.4 48.7 1.0 O2 A:EDO404 4.4 40.6 1.0 HB3 A:TRP318 4.5 39.8 1.0 C6N A:NAI401 4.5 33.7 1.0 O2D A:NAI401 4.5 37.1 1.0 HB3 A:HIS77 4.5 46.9 1.0 O7N A:NAI401 4.5 34.8 1.0 HD1 A:TRP318 4.6 40.4 1.0 O1 A:EDO404 4.6 42.5 1.0 H A:SER100 4.7 44.1 1.0 H72N A:NAI401 4.7 39.9 1.0 H42N A:NAI401 4.9 41.8 1.0 C2 A:EDO404 4.9 34.9 1.0 HA3 A:GLY101 4.9 44.9 1.0 CD1 A:TRP318 4.9 33.7 1.0 HO2N A:NAI401 5.0 44.5 1.0 H5N A:NAI401 5.0 40.8 1.0

Chlorine binding site 2 out of 2 in the Human CTBP1 (28-378)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human CTBP1 (28-378) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:65.4 occ:1.00 HE22 A:GLN218 1.9 61.1 1.0 NE2 A:GLN218 2.7 50.9 1.0 HE21 A:GLN218 3.2 61.1 1.0 CD A:GLN218 3.7 50.0 1.0 OE1 A:GLN218 3.8 52.4 1.0 O A:HOH595 3.8 46.7 1.0 HD2 A:HIS229 4.1 60.8 1.0 CD2 A:HIS229 4.2 50.7 1.0 HD21 A:LEU201 4.4 53.9 1.0 HD11 A:LEU201 4.4 50.8 1.0 NE2 A:HIS229 4.5 51.8 1.0 HD22 A:LEU201 4.7 53.9 1.0 CG A:HIS229 4.7 49.0 1.0 HD13 A:LEU201 4.8 50.8 1.0 HB3 A:HIS229 4.9 51.7 1.0

A.G.Bellesis, A.M.Jecrois, J.A.Hayes, C.A.Schiffer, W.E.Royer. Assembly of Human C-Terminal Binding Protein (Ctbp) Into Tetramers. J. Biol. Chem. V. 293 9101 2018.
ISSN: ESSN 1083-351X
PubMed: 29700119
DOI: 10.1074/JBC.RA118.002514