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Chlorine in PDB 6ch4: Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and MagnesiumEnzymatic activity of Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium
All present enzymatic activity of Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium:
2.7.1.190; Protein crystallography data
The structure of Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium, PDB code: 6ch4
was solved by
S.J.Caldwell,
A.M.Berghuis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ch4:
The structure of Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium
(pdb code 6ch4). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium, PDB code: 6ch4: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 6ch4Go back to Chlorine Binding Sites List in 6ch4
Chlorine binding site 1 out
of 3 in the Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 6ch4Go back to Chlorine Binding Sites List in 6ch4
Chlorine binding site 2 out
of 3 in the Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 6ch4Go back to Chlorine Binding Sites List in 6ch4
Chlorine binding site 3 out
of 3 in the Aminoglycoside Phosphotransferase (2'')-Ia S376N Mutant in Complex with Gmppnp and Magnesium
Mono view Stereo pair view
Reference:
S.J.Caldwell,
A.M.Berghuis.
Plasticity of Aminoglycoside Binding to Antibiotic Kinase Aph(2′′)-Ia. Antimicrob. Agents V. 62 2018CHEMOTHER..
Page generated: Sat Dec 12 12:49:36 2020
ISSN: ESSN 1098-6596 PubMed: 29661878 DOI: 10.1128/AAC.00202-18 |
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