Chlorine in PDB 6ctz: Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia

The structure of Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia, PDB code: 6ctz was solved by C.A.Smith, S.B.Vakulenko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.09 / 1.34
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	77.169, 58.982, 70.853, 90.00, 90.00, 90.00
R / Rfree (%)	14.6 / 17.1

The structure of Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia (pdb code 6ctz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia, PDB code: 6ctz:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:21.0 occ:1.00 O A:HOH832 3.0 26.1 1.0 OG A:SER178 3.4 19.6 1.0 NH1 A:ARG175 3.6 15.7 1.0 CD A:ARG175 3.7 16.0 1.0 CZ A:PHE301 3.8 34.5 1.0 CB A:SER178 3.9 18.5 1.0 CG A:LEU174 3.9 21.9 1.0 CD2 A:LEU174 4.1 23.4 1.0 CE2 A:PHE301 4.3 34.5 1.0 CD1 A:LEU174 4.4 23.7 1.0 CZ A:ARG175 4.5 14.7 1.0 O A:LEU174 4.5 18.7 1.0 NE A:ARG175 4.5 15.0 1.0 CA A:ARG175 4.6 16.8 1.0 NH1 A:ARG260 4.6 18.4 1.0 CD2 A:LEU264 4.6 15.3 1.0 CG A:ARG175 4.7 16.9 1.0 C A:LEU174 4.7 18.6 1.0 N A:ARG175 4.8 17.5 1.0 CE1 A:PHE301 4.8 34.8 1.0

Chlorine binding site 2 out of 2 in the Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Gdp and Kanamycin Complex of Aph(2")-Iiia within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl406 b:52.0 occ:1.00 O A:HOH874 2.7 42.6 1.0 O A:HOH697 2.8 34.1 1.0 O A:HOH786 3.6 24.6 1.0 CG1 A:ILE149 3.7 19.6 1.0 CB A:PHE268 4.1 15.5 1.0 CD1 A:ILE149 4.3 19.9 1.0 CD1 A:LEU145 4.3 24.0 1.0 CD2 A:LEU152 4.4 23.8 1.0 CE1 A:TYR229 4.6 16.6 1.0 CD A:LYS148 4.7 26.7 1.0 CG A:LYS148 4.7 24.7 1.0 CE A:LYS148 4.8 28.1 1.0 CD2 A:PHE268 4.8 15.4 1.0 CG A:PHE268 4.9 14.7 1.0 CB A:ILE149 4.9 19.6 1.0 O A:HOH932 5.0 40.3 1.0

C.A.Smith, H.Frase, M.Toth, L.Maltz, N.K.Stewart, S.B.Vakulenko. Structural Basis For Diversity of the Phosphorylation Mechanisms of Aminoglycoside 2" Phosphotransferases To Be Published.