Chlorine in PDB 6cwg: Ricin Catalytic Subunit Bound Go A9 Vhh Antibody

All present enzymatic activity of Ricin Catalytic Subunit Bound Go A9 Vhh Antibody:
3.2.2.22;

The structure of Ricin Catalytic Subunit Bound Go A9 Vhh Antibody, PDB code: 6cwg was solved by M.J.Rudolph, N.Mantis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.22 / 2.60
Space group	P 31
Cell size a, b, c (Å), α, β, γ (°)	76.654, 76.654, 134.331, 90.00, 90.00, 120.00
R / Rfree (%)	22.3 / 26.2

The binding sites of Chlorine atom in the Ricin Catalytic Subunit Bound Go A9 Vhh Antibody (pdb code 6cwg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Ricin Catalytic Subunit Bound Go A9 Vhh Antibody, PDB code: 6cwg:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Ricin Catalytic Subunit Bound Go A9 Vhh Antibody


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Ricin Catalytic Subunit Bound Go A9 Vhh Antibody within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl301 b:0.9 occ:1.00 NE2 C:HIS40 4.3 73.8 1.0 CA C:GLN223 4.5 67.2 1.0 CE1 C:HIS40 4.5 67.5 1.0 CG C:GLN223 4.6 75.3 1.0 CA C:SER264 4.6 95.3 1.0 OG C:SER264 4.7 89.3 1.0 CB C:SER264 4.8 92.4 1.0 CB C:GLN223 4.9 76.5 1.0

Chlorine binding site 2 out of 2 in the Ricin Catalytic Subunit Bound Go A9 Vhh Antibody


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Ricin Catalytic Subunit Bound Go A9 Vhh Antibody within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl302 b:0.8 occ:1.00 NH1 C:ARG197 4.5 98.0 1.0 OE2 C:GLU146 4.7 99.6 1.0

M.J.Rudolph, D.J.Vance, S.Kelow, S.K.Angalakurthi, S.Nguyen, S.A.Davis, Y.Rong, C.R.Middaugh, D.D.Weis, R.Dunbrack Jr., J.Karanicolas, N.J.Mantis. Contribution of An Unusual CDR2 Element of A Single Domain Antibody in Ricin Toxin Binding Affinity and Neutralizing Activity. Protein Eng. Des. Sel. V. 31 277 2018.
ISSN: ESSN 1741-0134
PubMed: 30265352
DOI: 10.1093/PROTEIN/GZY022