Chlorine in PDB 6d0w: Structure of Human Transthyretin Complex with Analgesic Inhibitor

The structure of Structure of Human Transthyretin Complex with Analgesic Inhibitor, PDB code: 6d0w was solved by V.Cody, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.43 / 1.70
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	43.979, 85.405, 65.006, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 26.1

The structure of Structure of Human Transthyretin Complex with Analgesic Inhibitor also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Structure of Human Transthyretin Complex with Analgesic Inhibitor (pdb code 6d0w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure of Human Transthyretin Complex with Analgesic Inhibitor, PDB code: 6d0w:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Structure of Human Transthyretin Complex with Analgesic Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human Transthyretin Complex with Analgesic Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:24.1 occ:0.50 CL3' A:FQ7201 0.0 24.1 0.5 C3' A:FQ7201 1.7 24.4 0.5 C2' A:FQ7201 2.7 27.9 0.5 C4' A:FQ7201 2.7 24.3 0.5 C1' A:FQ7201 4.0 27.6 0.5 C5' A:FQ7201 4.0 26.5 0.5 CD2 A:LEU110 4.3 19.5 1.0 C6' A:FQ7201 4.5 27.5 0.5 C3 A:FQ7201 4.7 31.3 0.5

Chlorine binding site 2 out of 4 in the Structure of Human Transthyretin Complex with Analgesic Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Human Transthyretin Complex with Analgesic Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:30.0 occ:0.50 CL5' A:FQ7201 0.0 30.0 0.5 C5' A:FQ7201 1.7 26.5 0.5 C6' A:FQ7201 2.7 27.5 0.5 C4' A:FQ7201 2.7 24.3 0.5 O A:SER117 3.4 20.1 1.0 C A:SER117 3.7 19.4 1.0 N A:LEU110 3.8 16.6 1.0 CB A:SER117 3.9 19.1 1.0 N A:THR118 3.9 17.9 1.0 CB A:LEU110 3.9 19.3 1.0 CA A:THR118 3.9 17.8 1.0 C3' A:FQ7201 4.0 24.4 0.5 C1' A:FQ7201 4.0 27.6 0.5 O A:ALA108 4.0 18.0 1.0 N A:THR119 4.1 18.6 1.0 CG2 A:THR119 4.1 20.9 1.0 C A:THR118 4.1 21.6 1.0 C A:ALA109 4.3 19.0 1.0 C A:ALA108 4.3 19.2 1.0 CA A:ALA109 4.4 20.1 1.0 CA A:SER117 4.5 18.9 1.0 CB A:THR119 4.5 22.8 1.0 C2' A:FQ7201 4.5 27.9 0.5 CA A:LEU110 4.5 16.6 1.0 N A:ALA109 4.6 18.6 1.0 CB A:ALA108 4.7 19.8 1.0 O A:THR118 4.8 18.4 1.0 CA A:THR119 4.9 19.4 1.0 CD2 A:LEU110 5.0 19.5 1.0

Chlorine binding site 3 out of 4 in the Structure of Human Transthyretin Complex with Analgesic Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Human Transthyretin Complex with Analgesic Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl201 b:29.1 occ:0.50 CL3' B:FQ7201 0.0 29.1 0.5 C3' B:FQ7201 1.7 27.5 0.5 C2' B:FQ7201 2.7 32.5 0.5 C4' B:FQ7201 2.7 28.7 0.5 O B:SER117 3.5 20.3 1.0 N B:THR119 3.7 23.0 1.0 CG2 B:THR119 3.7 20.1 1.0 C B:SER117 3.8 23.0 1.0 O B:ALA108 3.9 21.0 1.0 CA B:THR118 3.9 20.3 1.0 C B:THR118 3.9 23.4 1.0 C5' B:FQ7201 4.0 30.0 0.5 C1' B:FQ7201 4.0 31.8 0.5 N B:THR118 4.0 19.0 1.0 N B:LEU110 4.1 17.1 1.0 CB B:SER117 4.1 22.8 1.0 CB B:THR119 4.1 22.6 1.0 C B:ALA108 4.2 18.3 1.0 CB B:LEU110 4.3 18.2 1.0 CA B:ALA109 4.4 19.0 1.0 CB B:ALA108 4.5 21.4 1.0 C B:ALA109 4.5 19.7 1.0 C6' B:FQ7201 4.5 31.2 0.5 N B:ALA109 4.5 18.6 1.0 CA B:THR119 4.6 22.1 1.0 C3 B:FQ7201 4.6 28.1 0.5 O B:THR118 4.6 20.1 1.0 CA B:SER117 4.7 22.1 1.0 CA B:LEU110 4.8 17.6 1.0 CA B:ALA108 5.0 19.5 1.0

Chlorine binding site 4 out of 4 in the Structure of Human Transthyretin Complex with Analgesic Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Human Transthyretin Complex with Analgesic Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl201 b:30.8 occ:0.50 CL5' B:FQ7201 0.0 30.8 0.5 C5' B:FQ7201 1.7 30.0 0.5 C4' B:FQ7201 2.7 28.7 0.5 C6' B:FQ7201 2.7 31.2 0.5 C1' B:FQ7201 4.0 31.8 0.5 C3' B:FQ7201 4.0 27.5 0.5 CD2 B:LEU110 4.2 22.6 1.0 C2' B:FQ7201 4.5 32.5 0.5

V.Cody, S.Richardson. Structural Analysis of Human Transthyretin Analgesic Inhibitor Complex To Be Published.