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Atomistry » Chlorine » PDB 6cua-6d31 » 6d1z » |
Chlorine in PDB 6d1z: Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One InhibitorEnzymatic activity of Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor
All present enzymatic activity of Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor, PDB code: 6d1z
was solved by
S.E.Greasley,
E.Johnson,
M.L.Kraus,
C.N.Cronin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6d1z:
The structure of Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor
(pdb code 6d1z). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor, PDB code: 6d1z: Chlorine binding site 1 out of 1 in 6d1zGo back to Chlorine Binding Sites List in 6d1z
Chlorine binding site 1 out
of 1 in the Crystal Structure of Tyrosine-Protein Kinase Receptor in Complex with 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor
Mono view Stereo pair view
Reference:
S.K.Bagal,
K.Omoto,
D.C.Blakemore,
P.J.Bungay,
J.G.Bilsland,
P.J.Clarke,
M.S.Corbett,
C.N.Cronin,
J.J.Cui,
R.Dias,
N.J.Flanagan,
S.E.Greasley,
R.Grimley,
E.Johnson,
D.Fengas,
L.Kitching,
M.L.Kraus,
I.Mcalpine,
A.Nagata,
G.J.Waldron,
J.S.Warmus.
Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted Trka Kinase Inhibitors. J. Med. Chem. V. 62 247 2019.
Page generated: Sat Jul 27 21:16:30 2024
ISSN: ISSN 1520-4804 PubMed: 29672039 DOI: 10.1021/ACS.JMEDCHEM.8B00280 |
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