Chlorine in PDB 6db0: N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue

Protein crystallography data

The structure of N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue, PDB code: 6db0 was solved by S.W.White, M.Yun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 31.40 / 1.70
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 114.316, 55.796, 68.363, 90.00, 94.58, 90.00
R / Rfree (%) 16.4 / 18.8

Chlorine Binding Sites:

The binding sites of Chlorine atom in the N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue (pdb code 6db0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue, PDB code: 6db0:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 6db0

Go back to Chlorine Binding Sites List in 6db0
Chlorine binding site 1 out of 2 in the N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl302

b:89.3
occ:1.00
CL2 A:G3J302 0.0 89.3 1.0
C05 A:G3J302 1.8 83.3 1.0
C04 A:G3J302 2.8 79.3 1.0
C08 A:G3J302 2.8 81.7 1.0
N09 A:G3J302 3.0 79.0 1.0
O A:HOH465 3.9 51.3 1.0
C03 A:G3J302 4.1 79.1 1.0
C07 A:G3J302 4.1 77.8 1.0
O A:HOH403 4.3 50.8 1.0
C10 A:G3J302 4.4 77.1 1.0
C06 A:G3J302 4.6 78.4 1.0
O A:HOH454 4.7 27.1 1.0
C11 A:G3J302 4.9 77.1 1.0

Chlorine binding site 2 out of 2 in 6db0

Go back to Chlorine Binding Sites List in 6db0
Chlorine binding site 2 out of 2 in the N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl301

b:81.1
occ:1.00
CL2 B:G3J301 0.0 81.1 1.0
C05 B:G3J301 1.8 76.1 1.0
C08 B:G3J301 2.8 70.1 1.0
C04 B:G3J301 2.8 71.2 1.0
N09 B:G3J301 3.0 69.9 1.0
O B:HOH443 3.5 53.5 1.0
O B:HOH462 3.6 50.0 1.0
C03 B:G3J301 4.1 70.7 1.0
C07 B:G3J301 4.1 69.6 1.0
C10 B:G3J301 4.4 69.4 1.0
C06 B:G3J301 4.6 69.9 1.0
O B:HOH461 4.6 29.4 1.0
C11 B:G3J301 5.0 69.7 1.0

Reference:

S.W.White, M.Yun. N-Terminal Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue To Be Published.
Page generated: Sat Dec 12 12:52:38 2020

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