Chlorine in PDB 6ez2: Human Butyrylcholinesterase Carbamylated.

All present enzymatic activity of Human Butyrylcholinesterase Carbamylated.:
3.1.1.8;

The structure of Human Butyrylcholinesterase Carbamylated., PDB code: 6ez2 was solved by X.Brazzolotto, E.De La Mora, S.N.Dighe, B.P.Ross, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.97 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	76.010, 79.940, 231.490, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 22.3

The binding sites of Chlorine atom in the Human Butyrylcholinesterase Carbamylated. (pdb code 6ez2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Butyrylcholinesterase Carbamylated., PDB code: 6ez2:

Chlorine binding site 1 out of 1 in the Human Butyrylcholinesterase Carbamylated.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Butyrylcholinesterase Carbamylated. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl610 b:0.6 occ:1.00 NZ A:LYS314 3.1 64.6 1.0 O A:HOH747 3.4 51.5 1.0 CG A:LYS314 3.7 36.5 1.0 O A:PHE312 3.8 47.7 1.0 CE A:LYS314 4.1 55.9 1.0 CD A:LYS314 4.6 44.5 1.0 O A:GLY310 4.9 54.6 1.0 C A:PHE312 4.9 47.7 1.0 CB A:LYS314 4.9 50.2 1.0

S.N.Dighe, E.De La Mora, S.Chan, S.Kantham, M.Mccoll, S.K.Veliyath, J.A.Miles, Z.Nessar, R.P.Mcgeary, I.Silman, M.O.Parat, M.Weik, X.Brazzolotto, B.P.Ros. Rivastigmine and Metabolite Analogues with Putative Alzheimer'S Disease-Modifying Properties in A Caenorhabditis Elegans Model. Commun Chem 2019.
ISSN: ESSN 2399-3669
DOI: 10.1038/S42004-019-0133-4