Chlorine in PDB 6fac: Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp

The structure of Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp, PDB code: 6fac was solved by A.Schmitt, F.Hamann, P.Neumann, R.Ficner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.41 / 2.05
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	122.740, 67.320, 95.620, 90.00, 106.46, 90.00
R / Rfree (%)	21.6 / 24.4

The structure of Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp (pdb code 6fac). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp, PDB code: 6fac:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1003 b:42.5 occ:1.00 N A:ARG353 3.2 36.6 1.0 O A:HOH1213 3.3 38.6 1.0 N A:VAL354 3.3 39.3 1.0 CD1 A:ILE574 3.4 44.0 1.0 OG A:SER547 3.5 49.1 1.0 CB A:ARG352 3.5 38.7 1.0 CG2 A:VAL354 3.6 37.7 1.0 CA A:SER547 3.6 36.2 1.0 C A:ARG352 3.7 31.4 1.0 CB A:SER547 3.7 36.1 1.0 CA A:ARG352 3.8 32.9 1.0 CB A:VAL354 3.9 40.2 1.0 CA A:ARG353 4.0 44.2 1.0 CG1 A:ILE574 4.0 44.8 1.0 CB A:ARG353 4.0 38.6 1.0 O A:SER547 4.1 43.6 1.0 C A:ARG353 4.1 43.2 1.0 CA A:VAL354 4.2 42.2 1.0 CG A:ARG352 4.3 46.7 1.0 O A:HOH1280 4.3 54.1 1.0 C A:SER547 4.3 35.0 1.0 N A:SER547 4.5 32.2 1.0 O A:ARG352 4.7 34.2 1.0 CD A:ARG352 4.8 52.6 1.0 O A:HOH1314 4.9 62.5 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1004 b:91.2 occ:1.00 O A:ALA301 3.7 56.3 1.0 O A:HOH1160 4.6 65.0 1.0 C A:ALA301 4.6 57.9 1.0 CE1 A:TYR302 4.7 68.4 1.0 CZ A:TYR302 4.7 71.5 1.0 CB A:ALA301 4.9 61.8 1.0 CD1 A:TYR302 4.9 65.0 1.0 CE2 A:TYR302 5.0 68.7 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1005 b:0.6 occ:1.00 N A:MET723 2.9 31.9 1.0 CB A:MET723 3.1 37.7 1.0 CB A:GLU721 3.2 60.4 1.0 CG A:GLU721 3.2 82.0 1.0 OE1 A:GLU721 3.3 0.1 1.0 CE A:MET723 3.3 49.3 1.0 CG A:MET723 3.3 50.0 1.0 CD A:GLU721 3.4 98.2 1.0 N A:PRO722 3.5 44.7 1.0 CA A:MET723 3.6 40.0 1.0 C A:GLU721 3.6 46.0 1.0 CE A:MET695 3.7 81.2 1.0 CD A:PRO722 3.8 46.1 1.0 O A:HOH1309 3.9 56.2 1.0 C A:PRO722 3.9 40.2 1.0 CA A:GLU721 3.9 49.2 1.0 SD A:MET723 4.1 58.0 1.0 O A:GLU721 4.2 36.8 1.0 CA A:PRO722 4.2 42.7 1.0 OE2 A:GLU721 4.3 97.5 1.0 N A:LEU724 4.4 46.5 1.0 O A:HOH1173 4.4 61.9 1.0 C A:MET723 4.5 42.2 1.0 CB A:PRO722 4.6 45.8 1.0 CG A:PRO722 4.8 43.8 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the Deah-Box Helicase PRP2 in Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1006 b:87.9 occ:1.00 O A:ALA337 3.7 70.7 1.0 CZ A:TYR339 4.3 62.6 1.0 CE1 A:TYR339 4.4 55.3 1.0 C A:GLY338 4.5 62.7 1.0 O A:GLY338 4.6 62.5 1.0 CA A:GLY338 4.6 64.1 1.0 CE2 A:TYR339 4.6 61.2 1.0 C A:ALA337 4.6 65.9 1.0 CD1 A:TYR339 4.6 54.0 1.0 OH A:TYR339 4.7 65.5 1.0 N A:TYR339 4.9 60.7 1.0 CD2 A:TYR339 4.9 59.8 1.0 CG A:TYR339 4.9 59.2 1.0

A.Schmitt, F.Hamann, P.Neumann, R.Ficner. Crystal Structure of the Spliceosomal Deah-Box Atpase PRP2. Acta Crystallogr D Struct V. 74 643 2018BIOL.
ISSN: ISSN 2059-7983
PubMed: 29968674
DOI: 10.1107/S2059798318006356