Atomistry » Chlorine » PDB 6frq-6g1n » 6fv4
Atomistry »
  Chlorine »
    PDB 6frq-6g1n »
      6fv4 »

Chlorine in PDB 6fv4: The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate

Enzymatic activity of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate

All present enzymatic activity of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate:
3.5.1.25;

Protein crystallography data

The structure of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate, PDB code: 6fv4 was solved by M.S.Ahangar, C.M.Furze, C.S.Guy, C.Cooper, K.S.Maskew, B.Graham, A.D.Cameron, E.Fullam, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 54.56 / 1.97
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 164.766, 54.437, 110.262, 90.00, 123.22, 90.00
R / Rfree (%) 18.4 / 23.5

Other elements in 6fv4:

The structure of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate also contains other interesting chemical elements:

Zinc (Zn) 2 atoms
Cadmium (Cd) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate (pdb code 6fv4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate, PDB code: 6fv4:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 6fv4

Go back to Chlorine Binding Sites List in 6fv4
Chlorine binding site 1 out of 2 in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl405

b:44.7
occ:1.00
 ZN A:ZN401 2.2 42.4 1.0
CD A:CD403 2.7 35.5 1.0
N2 A:16G402 3.0 48.5 0.8
C7 A:16G402 3.3 48.8 0.8
C8 A:16G402 3.3 46.3 0.8
NE2 A:HIS56 3.4 33.4 1.0
NE2 A:HIS58 3.5 41.4 1.0
OE1 A:GLU122 3.5 39.0 1.0
CB A:ALA267 3.6 32.6 1.0
CD2 A:HIS209 3.6 30.7 1.0
NE2 A:HIS209 3.6 33.2 1.0
C2 A:16G402 3.8 43.3 0.8
CE1 A:HIS56 3.9 32.4 1.0
C1 A:16G402 3.9 43.2 0.8
OE2 A:GLU122 4.0 38.2 1.0
O7 A:16G402 4.1 53.1 0.8
CD A:GLU122 4.2 38.4 1.0
CD2 A:HIS58 4.2 34.3 1.0
O1 A:16G402 4.3 41.5 0.8
CD2 A:HIS56 4.5 30.8 1.0
CE1 A:HIS58 4.6 36.5 1.0
CA A:ALA267 4.7 29.0 1.0
O A:ALA267 4.9 33.4 1.0
CE1 A:HIS209 4.9 32.3 1.0
CG A:HIS209 4.9 27.1 1.0

Chlorine binding site 2 out of 2 in 6fv4

Go back to Chlorine Binding Sites List in 6fv4
Chlorine binding site 2 out of 2 in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl404

b:30.5
occ:1.00
 ZN B:ZN401 2.2 27.0 1.0
CD B:CD403 2.6 27.8 1.0
CE1 B:HIS134 3.4 36.6 1.0
OE1 B:GLU122 3.5 32.7 1.0
O B:HOH579 3.6 31.3 1.0
CD2 B:HIS209 3.6 29.1 1.0
NE2 B:HIS134 3.6 29.8 1.0
NE2 B:HIS56 3.6 24.1 1.0
NE2 B:HIS58 3.6 30.8 1.0
NE2 B:HIS209 3.7 26.4 1.0
OE2 B:GLU122 3.7 33.1 1.0
CB B:ALA267 3.8 26.0 1.0
CD B:GLU122 4.0 30.7 1.0
CE1 B:HIS56 4.1 24.4 1.0
O B:HOH593 4.2 33.6 1.0
CD2 B:HIS58 4.2 26.7 1.0
CE B:MET269 4.5 29.6 0.4
CD2 B:HIS56 4.7 26.0 1.0
ND1 B:HIS134 4.7 41.4 1.0
CE1 B:HIS58 4.7 28.1 1.0
CG B:HIS209 4.9 25.4 1.0
CA B:ALA267 4.9 30.4 1.0
NE2 B:HIS188 4.9 22.8 1.0
O B:ALA267 4.9 27.8 1.0
CD2 B:HIS134 4.9 41.6 1.0
CE1 B:HIS209 5.0 27.9 1.0

Reference:

M.S.Ahangar, C.M.Furze, C.S.Guy, C.Cooper, K.S.Maskew, B.Graham, A.D.Cameron, E.Fullam. Structural and Functional Determination of Homologs of Themycobacterium Tuberculosis N-Acetylglucosamine-6-Phosphate Deacetylase (Naga). J. Biol. Chem. V. 293 9770 2018.
ISSN: ESSN 1083-351X
PubMed: 29728457
DOI: 10.1074/JBC.RA118.002597
Page generated: Sat Jul 27 23:34:06 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy