Chlorine in PDB 6h4k: Structure of the USP25 C-Terminal Domain

Enzymatic activity of Structure of the USP25 C-Terminal Domain

All present enzymatic activity of Structure of the USP25 C-Terminal Domain:
3.4.19.12;

Protein crystallography data

The structure of Structure of the USP25 C-Terminal Domain, PDB code: 6h4k was solved by T.A.Klemm, F.Sauer, C.Kisker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.50 / 2.05
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 87.008, 87.008, 86.790, 90.00, 90.00, 90.00
R / Rfree (%) 19.2 / 22.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of the USP25 C-Terminal Domain (pdb code 6h4k). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the USP25 C-Terminal Domain, PDB code: 6h4k:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 6h4k

Go back to Chlorine Binding Sites List in 6h4k
Chlorine binding site 1 out of 2 in the Structure of the USP25 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the USP25 C-Terminal Domain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1101

b:67.6
occ:1.00
O A:HOH1255 2.1 74.4 1.0
O A:THR796 2.6 51.7 1.0
CL A:CL1102 2.8 55.6 1.0
C A:THR796 3.8 59.4 1.0
OG1 A:THR796 4.2 48.2 1.0
N A:THR796 4.3 64.1 1.0
O A:PRO797 4.5 49.0 1.0
C A:PRO797 4.5 53.2 1.0
CA A:THR796 4.6 62.5 1.0
N A:PRO797 4.8 58.4 1.0
N A:PRO798 4.8 56.8 1.0
CA A:PRO797 4.9 57.5 1.0
O A:HOH1227 5.0 62.8 1.0

Chlorine binding site 2 out of 2 in 6h4k

Go back to Chlorine Binding Sites List in 6h4k
Chlorine binding site 2 out of 2 in the Structure of the USP25 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the USP25 C-Terminal Domain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1102

b:55.6
occ:1.00
O A:HOH1255 2.7 74.4 1.0
CL A:CL1101 2.8 67.6 1.0
O A:THR800 2.8 49.2 1.0
O A:PRO797 2.9 49.0 1.0
OG1 A:THR796 2.9 48.2 1.0
O A:THR796 3.1 51.7 1.0
O A:HOH1227 3.2 62.8 1.0
C A:PRO797 3.6 53.2 1.0
C A:THR796 3.7 59.4 1.0
CB A:THR796 3.9 54.9 1.0
CA A:PRO798 4.0 54.2 1.0
C A:THR800 4.0 48.6 1.0
N A:PRO798 4.2 56.8 1.0
CA A:THR796 4.3 62.5 1.0
C A:PRO798 4.4 51.6 1.0
N A:PRO797 4.4 58.4 1.0
O A:HOH1249 4.4 61.3 1.0
O A:PRO798 4.4 56.4 1.0
CA A:PRO797 4.5 57.5 1.0
O A:HOH1234 4.6 46.4 1.0
N A:THR800 4.7 44.9 1.0
N A:THR796 4.7 64.1 1.0
CA A:ASP801 4.7 45.7 1.0
N A:ASP801 4.8 45.6 1.0
O A:HOH1214 4.8 56.0 1.0
CA A:THR800 4.9 47.5 1.0

Reference:

F.Sauer, T.Klemm, R.B.Kollampally, I.Tessmer, R.K.Nair, N.Popov, C.Kisker. Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Mol.Cell V. 74 421 2019.
ISSN: ISSN 1097-2765
PubMed: 30926243
DOI: 10.1016/J.MOLCEL.2019.02.029
Page generated: Sat Dec 12 13:03:49 2020

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