|
Chlorine in PDB 6h4w: Crystal Structure of Human KDM4A in Complex with Compound 19DProtein crystallography data
The structure of Crystal Structure of Human KDM4A in Complex with Compound 19D, PDB code: 6h4w
was solved by
Y.V.Le Bihan,
R.L.M.Van Montfort,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6h4w:
The structure of Crystal Structure of Human KDM4A in Complex with Compound 19D also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human KDM4A in Complex with Compound 19D
(pdb code 6h4w). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human KDM4A in Complex with Compound 19D, PDB code: 6h4w: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6h4wGo back to Chlorine Binding Sites List in 6h4w
Chlorine binding site 1 out
of 2 in the Crystal Structure of Human KDM4A in Complex with Compound 19D
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6h4wGo back to Chlorine Binding Sites List in 6h4w
Chlorine binding site 2 out
of 2 in the Crystal Structure of Human KDM4A in Complex with Compound 19D
Mono view Stereo pair view
Reference:
Y.V.Le Bihan,
R.M.Lanigan,
B.Atrash,
M.G.Mclaughlin,
S.Velupillai,
A.G.Malcolm,
K.S.England,
G.F.Ruda,
N.Y.Mok,
A.Tumber,
K.Tomlin,
H.Saville,
E.Shehu,
C.Mcandrew,
L.Carmichael,
J.M.Bennett,
F.Jeganathan,
P.Eve,
A.Donovan,
A.Hayes,
F.Wood,
F.I.Raynaud,
O.Fedorov,
P.E.Brennan,
R.Burke,
R.L.M.Van Montfort,
O.W.Rossanese,
J.Blagg,
V.Bavetsias.
C8-Substituted Pyrido[3,4-D]Pyrimidin-4(3H)-Ones: Studies Towards the Identification of Potent, Cell Penetrant Jumonji C Domain Containing Histone Lysine Demethylase 4 Subfamily (KDM4) Inhibitors, Compound Profiling in Cell-Based Target Engagement Assays. Eur.J.Med.Chem. V. 177 316 2019.
Page generated: Sat Dec 12 13:04:08 2020
ISSN: ISSN 0223-5234 PubMed: 31158747 DOI: 10.1016/J.EJMECH.2019.05.041 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |