Chlorine in PDB 6hek: Structure of Human USP28 Bound to Ubiquitin-Pa

Enzymatic activity of Structure of Human USP28 Bound to Ubiquitin-Pa

All present enzymatic activity of Structure of Human USP28 Bound to Ubiquitin-Pa:
3.4.19.12;

Protein crystallography data

The structure of Structure of Human USP28 Bound to Ubiquitin-Pa, PDB code: 6hek was solved by M.Gersch, D.Komander, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 143.05 / 3.03
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 103.205, 199.792, 204.905, 90.00, 90.00, 90.00
R / Rfree (%) 21.8 / 23.7

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Human USP28 Bound to Ubiquitin-Pa (pdb code 6hek). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Human USP28 Bound to Ubiquitin-Pa, PDB code: 6hek:

Chlorine binding site 1 out of 1 in 6hek

Go back to Chlorine Binding Sites List in 6hek
Chlorine binding site 1 out of 1 in the Structure of Human USP28 Bound to Ubiquitin-Pa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human USP28 Bound to Ubiquitin-Pa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl803

b:0.2
occ:0.50
OE2 A:GLU299 3.3 0.8 1.0
CD A:GLU299 4.4 0.4 1.0
OE1 A:GLU299 4.7 75.4 1.0

Reference:

M.Gersch, J.L.Wagstaff, A.V.Toms, B.Graves, S.M.V.Freund, D.Komander. Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity. Mol.Cell V. 74 436 2019.
ISSN: ISSN 1097-2765
PubMed: 30926242
DOI: 10.1016/J.MOLCEL.2019.02.030
Page generated: Sat Dec 12 13:04:51 2020

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