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Chlorine in PDB 6hme: Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27
Enzymatic activity of Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27
All present enzymatic activity of Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27:
2.7.11.1;
2.7.11.1;
Protein crystallography data
The structure of Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27, PDB code: 6hme
was solved by
K.Niefind,
D.Lindenblatt,
J.Jose,
M.Le Borgne,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 89.36 / 1.85 |
| Space group | P 43 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 126.370, 126.370, 124.630, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 17.5 / 19.7 |
Other elements in 6hme:
The structure of Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27 also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27
(pdb code 6hme). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27, PDB code: 6hme:
In total only one binding site of Chlorine was determined in the Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27, PDB code: 6hme:
Chlorine binding site 1 out of 1 in 6hme
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Chlorine Binding Sites List in 6hme
Chlorine binding site 1 out
of 1 in the Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Low-Salt Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA; CSNK2A1 Gene Product) in Complex with the Indenoindole-Type Inhibitor THN27 within 5.0Å range:
|
Reference:
D.Lindenblatt,
A.Nickelsen,
V.M.Applegate,
J.Hochscherf,
B.Witulski,
Z.Bouaziz,
C.Marminon,
M.Bretner,
M.Le Borgne,
J.Jose,
K.Niefind.
Diacritic Binding of An Indenoindole Inhibitor By CK2 Alpha Paralogs Explored By A Reliable Path to Atomic Resolution CK2 Alpha ' Structures. Acs Omega V. 4 5471 2019.
ISSN: ESSN 2470-1343
PubMed: 31559376
DOI: 10.1021/ACSOMEGA.8B03415
Page generated: Sun Jul 28 00:57:40 2024
ISSN: ESSN 2470-1343
PubMed: 31559376
DOI: 10.1021/ACSOMEGA.8B03415
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