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Chlorine in PDB 6htp: Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7Enzymatic activity of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7
All present enzymatic activity of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7:
3.4.25.1; Protein crystallography data
The structure of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7, PDB code: 6htp
was solved by
E.M.Huber,
M.Groll,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6htp:
The structure of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7
(pdb code 6htp). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7, PDB code: 6htp: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6htpGo back to Chlorine Binding Sites List in 6htp
Chlorine binding site 1 out
of 2 in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6htpGo back to Chlorine Binding Sites List in 6htp
Chlorine binding site 2 out
of 2 in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 7
Mono view Stereo pair view
Reference:
B.T.Xin,
E.M.Huber,
G.De Bruin,
W.Heinemeyer,
E.Maurits,
C.Espinal,
Y.Du,
M.Janssens,
E.S.Weyburne,
A.F.Kisselev,
B.I.Florea,
C.Driessen,
G.A.Van Der Marel,
M.Groll,
H.S.Overkleeft.
Structure-Based Design of Inhibitors Selective For Human Proteasome Beta 2C or Beta 2I Subunits. J.Med.Chem. V. 62 1626 2019.
Page generated: Sat Dec 12 13:06:32 2020
ISSN: ISSN 0022-2623 PubMed: 30657666 DOI: 10.1021/ACS.JMEDCHEM.8B01884 |
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