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Chlorine in PDB 6huc: Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18Enzymatic activity of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18
All present enzymatic activity of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18:
3.4.25.1; Protein crystallography data
The structure of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18, PDB code: 6huc
was solved by
E.M.Huber,
M.Groll,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6huc:
The structure of Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18
(pdb code 6huc). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18, PDB code: 6huc: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6hucGo back to Chlorine Binding Sites List in 6huc
Chlorine binding site 1 out
of 2 in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6hucGo back to Chlorine Binding Sites List in 6huc
Chlorine binding site 2 out
of 2 in the Yeast 20S Proteasome with Human BETA2C (S171G) in Complex with 18
Mono view Stereo pair view
Reference:
B.T.Xin,
E.M.Huber,
G.De Bruin,
W.Heinemeyer,
E.Maurits,
C.Espinal,
Y.Du,
M.Janssens,
E.S.Weyburne,
A.F.Kisselev,
B.I.Florea,
C.Driessen,
G.A.Van Der Marel,
M.Groll,
H.S.Overkleeft.
Structure-Based Design of Inhibitors Selective For Human Proteasome Beta 2C or Beta 2I Subunits. J.Med.Chem. V. 62 1626 2019.
Page generated: Sat Dec 12 13:06:53 2020
ISSN: ISSN 0022-2623 PubMed: 30657666 DOI: 10.1021/ACS.JMEDCHEM.8B01884 |
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