Chlorine in PDB 6huo: Cryoem Structure of Human Full-Length Heteromeric ALPHA1BETA3GAMMA2L Gaba(A)R in Complex with Alprazolam (Xanax), Gaba and Megabody MB38.

The binding sites of Chlorine atom in the Cryoem Structure of Human Full-Length Heteromeric ALPHA1BETA3GAMMA2L Gaba(A)R in Complex with Alprazolam (Xanax), Gaba and Megabody MB38. (pdb code 6huo). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryoem Structure of Human Full-Length Heteromeric ALPHA1BETA3GAMMA2L Gaba(A)R in Complex with Alprazolam (Xanax), Gaba and Megabody MB38., PDB code: 6huo:

Chlorine binding site 1 out of 1 in the Cryoem Structure of Human Full-Length Heteromeric ALPHA1BETA3GAMMA2L Gaba(A)R in Complex with Alprazolam (Xanax), Gaba and Megabody MB38.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryoem Structure of Human Full-Length Heteromeric ALPHA1BETA3GAMMA2L Gaba(A)R in Complex with Alprazolam (Xanax), Gaba and Megabody MB38. within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl501 b:36.6 occ:1.00 CLAB D:08H501 0.0 36.6 1.0 CAP D:08H501 1.7 36.6 1.0 CAJ D:08H501 2.7 36.6 1.0 CAH D:08H501 2.7 36.6 1.0 O D:HIS102 2.9 33.0 1.0 CB D:HIS102 3.6 33.0 1.0 CA D:HIS102 3.7 33.0 1.0 C D:HIS102 3.7 33.0 1.0 ND1 D:HIS102 3.8 33.0 1.0 CG D:HIS102 3.9 33.0 1.0 CZ C:PHE77 3.9 36.1 1.0 CAI D:08H501 4.0 36.6 1.0 CAS D:08H501 4.0 36.6 1.0 CE1 C:PHE77 4.2 36.1 1.0 ND2 C:ASN60 4.3 38.0 1.0 OD1 C:ASN60 4.3 38.0 1.0 CAU D:08H501 4.5 36.6 1.0 CG C:ASN60 4.5 38.0 1.0 CE2 D:PHE100 4.7 30.2 1.0 CE1 D:HIS102 4.8 33.0 1.0 CZ D:PHE100 4.8 30.2 1.0 CD2 D:HIS102 4.9 33.0 1.0 N D:ASN103 5.0 37.8 1.0

S.Masiulis, R.Desai, T.Uchanski, I.Serna Martin, D.Laverty, D.Karia, T.Malinauskas, J.Zivanov, E.Pardon, A.Kotecha, J.Steyaert, K.W.Miller, A.R.Aricescu. Gabaareceptor Signalling Mechanisms Revealed By Structural Pharmacology. Nature V. 565 454 2019.
ISSN: ISSN 0028-0836
PubMed: 30602790
DOI: 10.1038/S41586-018-0832-5