Chlorine in PDB 6hxf: Human STK10 Bound to A Maleimide Inhibitor

All present enzymatic activity of Human STK10 Bound to A Maleimide Inhibitor:
2.7.11.1;

The structure of Human STK10 Bound to A Maleimide Inhibitor, PDB code: 6hxf was solved by F.J.Sorrell, E.Salah, R.A.M.Serafim, P.A.Savitsky, T.Krojer, H.J.Bailey, D.Pinkas, N.A.Burgess-Brown, F.Von Delft, S.Knapp, C.Arrowsmith, C.Bountra, A.M.Edwards, J.M.Elkins, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	65.45 / 2.09
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	94.840, 101.670, 198.000, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 21.9

The binding sites of Chlorine atom in the Human STK10 Bound to A Maleimide Inhibitor (pdb code 6hxf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human STK10 Bound to A Maleimide Inhibitor, PDB code: 6hxf:

Chlorine binding site 1 out of 1 in the Human STK10 Bound to A Maleimide Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human STK10 Bound to A Maleimide Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:68.6 occ:1.00 O D:HOH655 3.2 53.1 1.0 O A:HIS149 3.3 29.1 1.0 CD2 A:TYR216 4.1 33.4 1.0 O D:HOH565 4.1 38.0 1.0 C A:HIS149 4.3 28.1 1.0 CE2 A:TYR216 4.3 31.9 1.0 CG A:TYR216 4.4 30.8 1.0 O D:HOH685 4.6 56.2 1.0 O A:HOH581 4.7 33.7 1.0 CD2 D:HIS291 4.7 30.1 1.0 O D:GLU290 4.7 36.8 1.0 CA D:HIS291 4.7 27.8 1.0 CB D:GLU290 4.8 35.2 1.0 CB A:HIS149 4.8 26.7 1.0 C D:GLU290 4.8 38.7 1.0 CB A:TYR216 4.9 26.4 1.0 CZ A:TYR216 4.9 30.9 1.0 N D:HIS291 4.9 28.4 1.0 CD1 A:TYR216 5.0 29.3 1.0 CA A:HIS149 5.0 27.8 1.0

F.J.Sorrell, E.Salah, R.A.M.Serafim, J.M.Elkins. Human STK10 Bound to A Maleimide Inhibitor To Be Published.