Chlorine in PDB 6i5c: Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex

The structure of Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex, PDB code: 6i5c was solved by S.Basu, V.Olieric, N.Matsugaki, Y.Kawano, T.Takashi, C.Y.Huang, F.Leonarski, Y.Yamada, L.Vera, N.Olieric, J.Basquin, J.A.Wojdyla, K.Diederichs, M.Yamamoto, O.Bunk, M.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.46 / 2.95
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.240, 156.830, 179.540, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 20.8

The structure of Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex also contains other interesting chemical elements:

Magnesium	(Mg)	3 atoms
Calcium	(Ca)	5 atoms

The binding sites of Chlorine atom in the Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex (pdb code 6i5c). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex, PDB code: 6i5c:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl504 b:92.4 occ:1.00 N A:LYS163 3.2 86.7 1.0 C A:TYR161 3.4 62.1 1.0 N A:GLY162 3.5 61.9 1.0 CD A:LYS164 3.5 71.8 1.0 CA A:TYR161 3.6 62.5 1.0 CB A:LYS163 3.7 87.1 1.0 CE A:LYS164 3.8 89.7 1.0 CA A:LYS163 3.9 84.8 1.0 O A:TYR161 4.0 73.1 1.0 CG A:LYS163 4.0 95.9 1.0 C A:GLY162 4.1 75.2 1.0 CA A:GLY162 4.2 70.2 1.0 O A:HOH681 4.4 70.8 1.0 N A:LYS164 4.4 88.9 1.0 C A:LYS163 4.5 82.0 1.0 CB A:TYR161 4.5 62.7 1.0 O A:ASP160 4.6 74.9 1.0 N A:TYR161 4.7 79.7 1.0 CG A:LYS164 4.9 65.2 1.0

Chlorine binding site 2 out of 2 in the Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Long Wavelength Native-Sad Phasing of Tubulin-Stathmin-Ttl Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl504 b:85.0 occ:1.00 O C:HOH800 3.3 57.0 1.0 O C:HOH761 3.3 63.1 1.0 N C:VAL363 3.3 65.3 1.0 NE2 C:GLN233 3.6 56.3 1.0 CB C:VAL362 3.6 66.2 1.0 CA C:VAL362 3.7 53.1 1.0 CB C:LEU368 4.0 53.7 1.0 CG1 C:VAL362 4.0 62.0 1.0 C C:VAL362 4.0 55.5 1.0 CB C:VAL363 4.3 63.9 1.0 CD1 C:LEU368 4.3 68.8 1.0 CA C:VAL363 4.3 62.3 1.0 O C:VAL363 4.4 73.3 1.0 CG2 C:VAL363 4.4 55.7 1.0 CG C:LEU368 4.5 55.9 1.0 CB C:ARG229 4.5 38.3 1.0 CD C:GLN233 4.5 55.7 1.0 CG C:GLN233 4.6 55.3 1.0 N C:LEU368 4.7 69.3 1.0 CG C:ARG229 4.8 58.6 1.0 CD C:ARG229 4.8 75.2 1.0 C C:VAL363 4.9 69.8 1.0 CA C:LEU368 4.9 45.6 1.0 CA C:GLY366 4.9 75.6 1.0 O C:THR361 5.0 59.3 1.0 CG2 C:VAL362 5.0 52.2 1.0

S.Basu, V.Olieric, F.Leonarski, N.Matsugaki, Y.Kawano, T.Takashi, C.Y.Huang, Y.Yamada, L.Vera, N.Olieric, J.Basquin, J.A.Wojdyla, O.Bunk, K.Diederichs, M.Yamamoto, M.Wang. Long-Wavelength Native-Sad Phasing: Opportunities and Challenges. Iucrj V. 6 373 2019.
ISSN: ESSN 2052-2525
PubMed: 31098019
DOI: 10.1107/S2052252519002756