Chlorine in PDB 6i81: Crystal Structure of the Second Bromodomain of BRD2 in Complex with RT56

The structure of Crystal Structure of the Second Bromodomain of BRD2 in Complex with RT56, PDB code: 6i81 was solved by S.Picaud, R.Traquete, G.J.L.Bernardes, J.Newman, C.H.Arrowsmith, A.M.Edwards, C.Bountra, P.Filippakopoulos, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.33 / 1.74
Space group	I 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	127.297, 127.297, 40.594, 90.00, 90.00, 90.00
R / Rfree (%)	17.2 / 19.6

The binding sites of Chlorine atom in the Crystal Structure of the Second Bromodomain of BRD2 in Complex with RT56 (pdb code 6i81). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Second Bromodomain of BRD2 in Complex with RT56, PDB code: 6i81:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Second Bromodomain of BRD2 in Complex with RT56


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Second Bromodomain of BRD2 in Complex with RT56 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl503 b:24.6 occ:1.00 CL1 A:H7E503 0.0 24.6 1.0 C25 A:H7E503 1.6 19.8 1.0 C24 A:H7E503 2.6 18.4 1.0 C26 A:H7E503 2.6 19.0 1.0 CB A:ASP434 3.7 23.3 1.0 C23 A:H7E503 3.9 18.1 1.0 C27 A:H7E503 3.9 18.3 1.0 CE A:MET438 3.9 25.8 1.0 O A:HOH601 4.4 42.2 1.0 OD2 A:ASP434 4.4 29.9 1.0 C22 A:H7E503 4.4 17.0 1.0 C A:ASP434 4.6 19.7 1.0 CG A:ASP434 4.6 31.6 1.0 N A:VAL435 4.6 18.1 1.0 SD A:MET438 4.6 22.9 1.0 CA A:ASP434 4.8 22.0 1.0 O A:ASP434 4.9 18.9 1.0 CZ2 A:TRP370 5.0 21.4 1.0

S.Picaud, R.Traquete, G.J.L.Bernardes, J.Newman, C.H.Arrowsmith, A.M.Edwards, C.Bountra, P.Filippakopoulos, Structural Genomics Consortium (Sgc). Crystal Structure of the Second Bromodomain of BRD2 in Complex with RT56 To Be Published.