Chlorine in PDB 6iey: Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex

All present enzymatic activity of Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex:
3.1.1.1;

The structure of Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex, PDB code: 6iey was solved by S.H.Kim, P.A.Kang, K.T.Han, S.W.Lee, S.K.Rhee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.04 / 2.10
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	118.463, 152.411, 44.137, 90.00, 90.00, 90.00
R / Rfree (%)	20.9 / 26.1

The binding sites of Chlorine atom in the Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex (pdb code 6iey). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex, PDB code: 6iey:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:85.0 occ:1.00 CL1 A:CLM401 0.0 85.0 1.0 C1 A:CLM401 1.8 58.5 1.0 CL2 A:CLM401 2.8 71.7 1.0 C2 A:CLM401 2.8 52.9 1.0 N2 A:CLM401 3.3 53.7 1.0 CD1 A:ILE85 3.7 18.9 1.0 CD1 B:PHE34 3.8 23.9 1.0 O2 A:CLM401 3.9 52.6 1.0 OH A:TYR202 3.9 54.2 1.0 CE1 B:PHE34 4.1 28.6 1.0 CZ A:TYR202 4.2 53.3 1.0 CG B:PHE34 4.5 22.8 1.0 CE2 A:TYR202 4.7 49.3 1.0 C3 A:CLM401 4.7 47.2 1.0 CE1 A:TYR202 4.8 50.0 1.0 CZ A:PHE211 4.8 19.4 1.0 CB B:PHE34 4.9 22.4 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Chloramphenicol-Metabolizaing Enzyme ESTDL136- Chloramphenicol Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:71.7 occ:1.00 CL2 A:CLM401 0.0 71.7 1.0 C1 A:CLM401 1.8 58.5 1.0 C2 A:CLM401 2.7 52.9 1.0 CL1 A:CLM401 2.8 85.0 1.0 O2 A:CLM401 3.3 52.6 1.0 CD1 A:LEU203 3.6 23.4 1.0 N2 A:CLM401 3.7 53.7 1.0 CB A:LEU203 4.2 27.6 1.0 CA A:LEU203 4.2 28.8 1.0 O A:TYR202 4.3 43.4 1.0 CE2 A:PHE211 4.4 23.8 1.0 CE2 A:TYR202 4.4 49.3 1.0 O A:HOH512 4.4 31.6 1.0 CG A:LEU203 4.5 33.4 1.0 CD2 A:TYR202 4.6 42.3 1.0 CZ A:TYR202 4.7 53.3 1.0 C A:TYR202 4.7 33.6 1.0 N A:LEU203 4.7 29.6 1.0 CZ A:PHE211 4.8 19.4 1.0 C3 A:CLM401 4.8 47.2 1.0 O A:HOH592 4.9 44.3 1.0 ND1 A:HIS279 4.9 25.1 1.0 CG A:TYR202 5.0 44.3 1.0

S.H.Kim, P.A.Kang, K.T.Han, S.W.Lee, S.K.Rhee. Crystal Structure of Chloramphenicol-Metabolizing Enzyme ESTDL136 From A Metagenome. Plos One V. 14 10298 2019.
ISSN: ESSN 1932-6203
PubMed: 30645605
DOI: 10.1371/JOURNAL.PONE.0210298