Chlorine in PDB 6iyu: Crystal Structure Analysis of An Eukaryotic Membrane Protein

The structure of Crystal Structure Analysis of An Eukaryotic Membrane Protein, PDB code: 6iyu was solved by X.H.Wang, Y.Zeng, M.Su, F.Gao, Y.H.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.72 / 2.20
Space group	P 63 2 2
Cell size a, b, c (Å), α, β, γ (°)	127.449, 127.449, 102.141, 90.00, 90.00, 120.00
R / Rfree (%)	19.8 / 21.7

The structure of Crystal Structure Analysis of An Eukaryotic Membrane Protein also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Chlorine atom in the Crystal Structure Analysis of An Eukaryotic Membrane Protein (pdb code 6iyu). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Crystal Structure Analysis of An Eukaryotic Membrane Protein, PDB code: 6iyu:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Crystal Structure Analysis of An Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure Analysis of An Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:42.7 occ:1.00 O A:HOH540 3.0 52.1 0.5 O A:HOH543 3.3 39.6 1.0 CD2 A:HIS142 4.3 41.2 1.0 CB A:HIS142 4.4 43.6 1.0 CG A:HIS142 4.5 42.8 1.0 O A:HOH518 4.6 49.9 0.5 ND1 A:HIS143 5.0 51.7 1.0

Chlorine binding site 2 out of 5 in the Crystal Structure Analysis of An Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure Analysis of An Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:59.4 occ:1.00 NZ A:LYS155 3.1 40.7 1.0 O A:HOH560 3.4 74.2 1.0 O A:HOH567 3.4 61.0 1.0 CA A:GLY133 3.6 35.2 1.0 CD A:LYS155 3.8 41.0 1.0 CD2 A:HIS136 3.8 63.9 1.0 N A:GLY133 3.9 45.6 1.0 CB A:HIS136 3.9 37.1 1.0 CE A:LYS155 3.9 44.5 1.0 O A:ALA132 3.9 46.5 1.0 C A:ALA132 4.1 39.9 1.0 CG A:LYS155 4.1 41.3 1.0 CG A:HIS136 4.2 59.0 1.0 CB A:ALA69 4.7 32.7 1.0 CG2 A:THR151 4.7 38.3 1.0 C A:GLY133 4.8 47.0 1.0 CB A:ALA132 4.8 34.5 1.0 O A:GLY133 4.9 42.0 1.0 CL A:CL406 4.9 62.1 1.0 NE2 A:HIS136 5.0 61.6 1.0

Chlorine binding site 3 out of 5 in the Crystal Structure Analysis of An Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure Analysis of An Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:80.9 occ:1.00 NH1 A:ARG170 3.2 55.1 1.0 NH2 A:ARG170 3.3 45.8 1.0 NE2 A:GLN167 3.4 69.4 1.0 CZ A:ARG170 3.7 52.2 1.0 CD A:PRO41 4.0 63.5 1.0 CG A:GLN167 4.2 57.1 1.0 CD A:GLN167 4.2 58.8 1.0 CG1 A:VAL172 4.4 48.5 1.0 CG A:PRO41 4.4 68.0 1.0 CG2 A:VAL172 5.0 50.2 1.0 NE A:ARG170 5.0 51.2 1.0 CB A:VAL172 5.0 55.7 1.0

Chlorine binding site 4 out of 5 in the Crystal Structure Analysis of An Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure Analysis of An Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:73.7 occ:1.00 N A:PHE52 3.3 52.5 1.0 CD A:PRO51 3.4 58.9 1.0 CB A:PHE52 3.5 53.0 1.0 CG A:PRO51 3.7 55.6 1.0 N A:PRO51 3.7 60.7 1.0 CA A:PHE52 4.1 55.0 1.0 C A:SER50 4.1 59.1 1.0 CA A:SER50 4.2 49.2 1.0 C A:PRO51 4.3 56.7 1.0 CA A:PRO51 4.5 53.6 1.0 CB A:PRO51 4.6 54.8 1.0 O A:SER50 4.8 55.1 1.0 O A:LYS49 4.8 65.3 1.0 N A:ALA53 4.9 45.2 1.0 CG A:PHE52 4.9 52.3 1.0 CB A:SER50 5.0 50.5 1.0

Chlorine binding site 5 out of 5 in the Crystal Structure Analysis of An Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure Analysis of An Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl406 b:62.1 occ:1.00 NZ A:LYS155 2.9 40.7 1.0 O A:HOH564 3.0 55.5 1.0 OH A:TYR66 3.4 67.9 1.0 CE1 A:TYR66 3.5 47.8 1.0 CB A:ALA132 3.6 34.5 1.0 CG A:LYS129 3.8 43.9 1.0 CE A:LYS155 3.8 44.5 1.0 CZ A:TYR66 3.9 47.8 1.0 CA A:LYS129 4.0 47.4 1.0 O A:HOH532 4.1 83.0 1.0 CB A:LYS129 4.3 39.0 1.0 O A:LYS129 4.6 41.7 1.0 CD1 A:TYR66 4.7 42.8 1.0 O A:ARG128 4.7 45.1 1.0 N A:LYS129 4.8 42.8 1.0 C A:LYS129 4.8 40.0 1.0 CL A:CL403 4.9 59.4 1.0 O A:HOH567 4.9 61.0 1.0

X.H.Wang, M.Su, F.Gao, W.Xie, Y.Zeng, D.L.Li, X.L.Liu, H.Zhao, L.Qin, F.Li, Q.Liu, O.B.Clarke, S.M.Lam, G.H.Shui, W.A.Hendrickson, Y.H.Chen. Structural Basis For Activity of Tric Counter-Ion Channels in Calcium Release. Proc.Natl.Acad.Sci.Usa V. 116 4238 2019.
ISSN: ESSN 1091-6490
PubMed: 30770441
DOI: 10.1073/PNAS.1817271116