Chlorine in PDB 6iz0: Crystal Structure Analysis of A Eukaryotic Membrane Protein

The structure of Crystal Structure Analysis of A Eukaryotic Membrane Protein, PDB code: 6iz0 was solved by X.H.Wang, Y.Zeng, F.Gao, M.Su, Y.H.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.59 / 2.30
Space group	P 63 2 2
Cell size a, b, c (Å), α, β, γ (°)	127.049, 127.049, 101.448, 90.00, 90.00, 120.00
R / Rfree (%)	21.9 / 24

The structure of Crystal Structure Analysis of A Eukaryotic Membrane Protein also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Chlorine atom in the Crystal Structure Analysis of A Eukaryotic Membrane Protein (pdb code 6iz0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Crystal Structure Analysis of A Eukaryotic Membrane Protein, PDB code: 6iz0:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:42.4 occ:0.90 O A:HOH538 3.0 52.6 0.5 O A:HOH531 3.2 42.9 1.0 CB A:HIS142 4.4 43.1 1.0 CD2 A:HIS142 4.4 42.5 1.0 O A:HOH518 4.5 44.0 0.5 CG A:HIS142 4.5 41.6 1.0 ND1 A:HIS143 5.0 55.4 1.0

Chlorine binding site 2 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:53.7 occ:0.70 NZ A:LYS155 3.2 49.6 1.0 ND1 A:HIS136 3.5 65.3 1.0 CA A:GLY133 3.7 40.9 1.0 CB A:HIS136 3.8 41.8 1.0 O A:ALA132 3.9 47.1 1.0 CD A:LYS155 4.0 50.5 1.0 N A:GLY133 4.0 48.1 1.0 CG A:HIS136 4.1 58.4 1.0 CE A:LYS155 4.1 52.4 1.0 CG A:LYS155 4.1 45.1 1.0 C A:ALA132 4.1 47.7 1.0 CB A:ALA69 4.4 35.0 1.0 CE1 A:HIS136 4.6 63.1 1.0 CG2 A:THR151 4.6 39.6 1.0 C A:GLY133 4.8 47.6 1.0 CB A:ALA132 4.9 36.1 1.0 O A:GLY133 4.9 50.4 1.0

Chlorine binding site 3 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:61.6 occ:0.50 NH2 A:ARG174 3.0 0.6 1.0 NH1 A:ARG170 3.2 62.0 1.0 NH1 A:ARG174 3.3 0.9 1.0 NH2 A:ARG170 3.5 57.9 1.0 NE2 A:GLN167 3.5 74.1 1.0 CZ A:ARG174 3.5 0.7 1.0 CZ A:ARG170 3.8 61.0 1.0 CD A:PRO41 4.0 66.8 1.0 CG A:GLN167 4.2 54.3 1.0 CD A:GLN167 4.2 62.1 1.0 CG A:PRO41 4.4 72.5 1.0 CG1 A:VAL172 4.4 60.2 1.0 NE A:ARG174 4.8 1.0 1.0 CB A:VAL172 5.0 63.2 1.0

Chlorine binding site 4 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:57.0 occ:0.50 CD A:PRO51 3.4 64.5 1.0 N A:PHE52 3.5 66.0 1.0 CB A:PHE52 3.6 55.2 1.0 CG A:PRO51 3.6 60.8 1.0 N A:PRO51 3.8 66.4 1.0 CA A:PHE52 4.2 59.6 1.0 C A:SER50 4.2 63.9 1.0 CA A:SER50 4.3 63.1 1.0 C A:PRO51 4.5 64.7 1.0 CA A:PRO51 4.6 61.6 1.0 CB A:PRO51 4.7 61.0 1.0 O A:LYS49 4.9 73.5 1.0 CG A:PHE52 4.9 65.1 1.0 N A:ALA53 5.0 56.8 1.0

Chlorine binding site 5 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl406 b:60.9 occ:0.60 NZ A:LYS155 3.0 49.6 1.0 OH A:TYR66 3.0 75.8 1.0 O A:HOH543 3.0 57.6 1.0 CB A:ALA132 3.5 36.1 1.0 CE1 A:TYR66 3.5 60.5 1.0 CZ A:TYR66 3.6 63.6 1.0 CE A:LYS155 3.8 52.4 1.0 CA A:ALA129 4.0 47.9 1.0 O A:HOH532 4.3 57.5 1.0 CB A:ALA129 4.3 38.7 1.0 O A:ALA129 4.6 49.5 1.0 O A:ARG128 4.6 53.3 1.0 CD1 A:TYR66 4.7 53.1 1.0 N A:ALA129 4.8 50.6 1.0 C A:ALA129 4.8 49.4 1.0 CE2 A:TYR66 4.8 58.9 1.0 CA A:ALA132 5.0 43.9 1.0

X.H.Wang, M.Su, F.Gao, W.Xie, Y.Zeng, D.L.Li, X.L.Liu, H.Zhao, L.Qin, F.Li, Q.Liu, O.B.Clarke, S.M.Lam, G.H.Shui, W.A.Hendrickson, Y.H.Chen. Structural Basis For Activity of Tric Counter-Ion Channels in Calcium Release. Proc.Natl.Acad.Sci.Usa V. 116 4238 2019.
ISSN: ESSN 1091-6490
PubMed: 30770441
DOI: 10.1073/PNAS.1817271116